LOCUS CCD64771.1 749 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Sodium/hydrogen exchanger protein. ACCESSION BX284606-1604 PROTEIN_ID CCD64771.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="nhx-4" /locus_tag="CELE_F14B8.1" /standard_name="F14B8.1a" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00003732" /db_xref="GOA:G5EDU2" /db_xref="InterPro:IPR004709" /db_xref="InterPro:IPR006153" /db_xref="InterPro:IPR018422" /db_xref="UniProtKB/TrEMBL:G5EDU2" /db_xref="WormBase:WBGene00003732" intron_pos 2:1 (1/12) intron_pos 29:1 (2/12) intron_pos 65:2 (3/12) intron_pos 117:1 (4/12) intron_pos 322:2 (5/12) intron_pos 390:2 (6/12) intron_pos 429:1 (7/12) intron_pos 499:0 (8/12) intron_pos 546:1 (9/12) intron_pos 576:2 (10/12) intron_pos 658:1 (11/12) intron_pos 703:1 (12/12) BEGIN 1 MRSQKTLLVI LTLLLSYNVF CTGDTNGTLA QDPADQLLNT VPENFTNNIE YPQNNNNNTS 61 ETDESMDAEG EWVQSAPPEE IEEAKHLLDP VHVDFEHTHK PLAFVFLIIL VTLAKPTLHW 121 PVLRKLPESV VLMLYGVLMA TAVKALMRID PGQLDTFMFF MILLPAIVND AGLSMQKKEF 181 TIALPKILLF AVVGTVVHAL LLAATMYGIE PIFSFKPGFL HLFVFATLIS AVDPVSVLST 241 FAELDVKKSL FILIFGESLC NDAVTIVLYR TSINVIKTSD ASDEMLTITS VVGSCVVQFM 301 IVCGFGLLCG AVVGFAGVFI MKNMVGHQMN QPIFQLFCPY LAYLLAETGH YSGILASILC 361 AAIMSYYMAA NMCVEMEFAA FTFSKTGSSL SESCIFFYLG VSLVSYNHEF DFYFIAVTVF 421 CCTLYRFLVT CTLSAFYNLF ASEKNRIPFT DQLVVTHAGI RGAVCFGLVQ IIDERIIPAK 481 PYFVTTTLAM IFVTSILQGC TIKFVMKCLK IPGDDGTKQK DPKALRWLTH LNDKYIKKFL 541 VSENTYLPTD ETFRNLGLPK AVSTALRIGE RSHTDLQRHG EVSHTPAPSV GRPTIAPFDF 601 GNMEEENNRL PSTGRRTPVA RSQTRYSRHF IYAIPNETDN YLTCPVSASK RPPFDPSQVY 661 QHQNTISNPG DDRARCYNRR HNSMSGADEM ELKQLNQTVQ KKLSRTITSG TKQFVVNPDE 721 AIREESPATI PKKRATFEDD EISKIDESE //