LOCUS CCD62782.1 435 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Dual specificity mitogen-activated protein kinase kinase jkk-1 protein. ACCESSION BX284606-1209 PROTEIN_ID CCD62782.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="jkk-1" /locus_tag="CELE_F35C8.3" /standard_name="F35C8.3" /note="Confirmed by transcript evidence" /db_xref="EnsemblGenomes-Gn:WBGene00002177" /db_xref="EnsemblGenomes-Tr:F35C8.3" /db_xref="GOA:G5EDT6" /db_xref="InterPro:IPR000719" /db_xref="InterPro:IPR008271" /db_xref="InterPro:IPR011009" /db_xref="UniProtKB/Swiss-Prot:G5EDT6" /db_xref="WormBase:WBGene00002177" intron_pos 12:1 (1/11) intron_pos 48:1 (2/11) intron_pos 75:1 (3/11) intron_pos 112:1 (4/11) intron_pos 150:0 (5/11) intron_pos 189:0 (6/11) intron_pos 241:0 (7/11) intron_pos 296:0 (8/11) intron_pos 350:0 (9/11) intron_pos 381:0 (10/11) intron_pos 401:0 (11/11) BEGIN 1 MENVCFQQRL RDLETRVRKW KFLKLGLTEV RLRPRDRRST SVDQKHKECS STSSSPQHQR 61 PNNIGYLTSP MERKFTPLSM KPSPSRRDTE KDALEYEFLE GYKKSGTLEI DGEKQVVDPN 121 EIHIISLLGS GSCGVVESAT VRSKLMAVKT MYKNDNKENL KRILRDVRIM SMCNSPFIVT 181 SYGYFMFDSS VKICMQIMSA CCEKLLRRIY HSKLDFFPEF VAGHIVYSAI SALDYLKEKH 241 SIIHRDIKPS NILFDDSGNV KLCDFGISGF MTDSMAHSKS AGCPPYMAPE RLTIETNSKY 301 DVRSDVWSLG ITVYQLVTGL YPFPLNDMEF TTLTIIANLN LPSPSLREET KRSFSPLFIE 361 FLDLCLRKDV RERPEYRQLM KHDFYLDYDP ASGSAYKFKA INGKCNQVAD WFVDVIRLSK 421 TEDELKSIPN TPCVN //