LOCUS       CCD61459.1               642 aa    PRT              CON 06-FEB-2024
DEFINITION  Caenorhabditis elegans Probable methylenetetrahydrofolate
            reductase (NADPH) protein.
ACCESSION   BX284602-2794
PROTEIN_ID  CCD61459.1
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
            Caenorhabditis.
REFERENCE   1  (bases 1 to 15279421)
  AUTHORS   WormBase.
  CONSRTM   WormBase Consortium
  JOURNAL   Submitted (04-FEB-2024) to the INSDC. WormBase Group, European
            Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email:
            help@wormbase.org
REFERENCE   2  (bases 1 to 15279421)
  AUTHORS   Sulson J.E., Waterston R.
  JOURNAL   Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project:
            Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome
            Institute at Washington University, St. Louis, MO 63110, USA.
REFERENCE   3  (bases 1 to 15279421)
  AUTHORS   Sulson J.E., Waterston R.
  CONSRTM   Caenorhabditis elegans Sequencing Consortium
  TITLE     Genome sequence of the nematode C. elegans: a platform for
            investigating biology
  JOURNAL   Science 282(5396), 2012-2018(1998).
COMMENT     Annotated features correspond to WormBase release WS292.
            Protein-coding gene structures below are the result of integration
            and manual review of the following types of data: ab initio
            predictions by Genefinder (P. Green and L. Hillier, pers. comm.);
            alignments to published proteins and cDNAs; genome sequence
            conservation with other nematodes (e.g. to C. briggsae using WABA:
            Genome Res. 2000. 10:1115-1125); sequence features (such as
            trans-splice and polyA sites).
            Sources of data: large-scale EST projects of Yuji Kohara
            (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome
            cloning project (http://worfdb.dfci.harvard.edu); RST large-scale
            sequencing project (Genome Res. 2009. 19:2334-2342); IST library
            (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010
            Unpublished); UTRome EST data submission (UTRome v1 Mangone M.
            Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep
            sequencing data (454 read clusters - Makedonka Mitreva,
            unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66);
            Numerous data sets from the modENCODE project (Science. 2010.
            330:1775-87); Individual C. elegans Nucleotide Database
            submissions; Personal communications with C. elegans researchers;
            Non-Coding gene structures below are derived using the following
            methods and data: ab initio prediction of tRNAs by tRNAscan-SE
            (Nucl. Acids. Res., 25, 955-964); integration and appraisal of
            miRNAs from miRBase (http://www.mirbase.org); integration and
            appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell.
            2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87);
            manual curation of novel published ncRNAs from the literature.
FEATURES             Qualifiers
     source          /organism="Caenorhabditis elegans"
                     /chromosome="II"
                     /strain="Bristol N2"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:6239"
     protein         /transl_table=1
                     /gene="mthf-1"
                     /locus_tag="CELE_C06A8.1"
                     /standard_name="C06A8.1b"
                     /note="Confirmed by transcript evidence"
                     /db_xref="EnsemblGenomes-Gn:WBGene00015512"
                     /db_xref="EnsemblGenomes-Tr:C06A8.1a"
                     /db_xref="WormBase:WBGene00015512"
     intron_pos      7:2 (1/6)
     intron_pos      32:2 (2/6)
     intron_pos      157:0 (3/6)
     intron_pos      403:0 (4/6)
     intron_pos      541:0 (5/6)
     intron_pos      592:2 (6/6)
BEGIN
        1 MAVLSKNGVE TDENAVVEEK ITLESGKSWS PKHYELLHER IERLIDEKQQ FFSLEFFPPR
       61 FVNGVPNFLE RVERLSEGGS VFVDMTWHMG SDPANVDKVT SSSSIAASML DYCGVDTMLH
      121 MTCVQYNKAD TLKHLEQAKA MGLRSILALR GDLPPGTELE DTHQFRALDM IRWIREEYGN
      181 YFSIGCAGYP LGHPQAPSYK ADLMYLKAKC DAGANFVITQ LFFEAETFEK FVRDCREIGI
      241 TQPIIPGIMP IMGYESIKRI AKLSQLEIPQ HILDDLEPIK HDDDAVQKYG TERCIEMCRR
      301 LLDNGTAPSI HLYTMNREGS IREILKSLGL WKLEGDRVFP WKNRSQHPIR CLESVRPIYW
      361 SFRPRSYITR TRDWDQFPNG RWGNSSSPAF GDVSSYYLSN LTTVRNADDR LAMFGANIES
      421 FEDVKRVFIN YITQAPNADG VKVTVLPWTE AETGVQPETS LISEQLVWCN ENGILTVNSQ
      481 PSVNGAPSTD PLVGWGKPGG YCYQKAYLEC FMTAELSDKL IQIIEREFPV RVNYHAINKD
      541 STFDKTNSEE TTPIAVTWGV FPGSEIAQPT VVDPLSFRAW RDEAYQMWMA QWGDFYPKES
      601 KSYGVIKAVH DEFRLVTLVD NDFQKPSVLF DVLQKALDEL KK
//