LOCUS CAC42283.1 694 aa PRT CON 06-FEB-2024 DEFINITION Caenorhabditis elegans Nuclear hormone receptor family member daf-12 protein. ACCESSION BX284606-2523 PROTEIN_ID CAC42283.1 SOURCE Caenorhabditis elegans ORGANISM Caenorhabditis elegans Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. REFERENCE 1 (bases 1 to 17718942) AUTHORS WormBase. CONSRTM WormBase Consortium JOURNAL Submitted (04-FEB-2024) to the INSDC. WormBase Group, European Bioinformatics Institute, Cambridge, CB10 1SA, UK. Email: help@wormbase.org REFERENCE 2 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. JOURNAL Submitted (03-MAR-2003) to the INSDC. Nematode Sequencing Project: Sanger Institute, Hinxton, Cambridge CB10 1SA, UK and The Genome Institute at Washington University, St. Louis, MO 63110, USA. REFERENCE 3 (bases 1 to 17718942) AUTHORS Sulson J.E., Waterston R. CONSRTM Caenorhabditis elegans Sequencing Consortium TITLE Genome sequence of the nematode C. elegans: a platform for investigating biology JOURNAL Science 282(5396), 2012-2018(1998). COMMENT Annotated features correspond to WormBase release WS292. Protein-coding gene structures below are the result of integration and manual review of the following types of data: ab initio predictions by Genefinder (P. Green and L. Hillier, pers. comm.); alignments to published proteins and cDNAs; genome sequence conservation with other nematodes (e.g. to C. briggsae using WABA: Genome Res. 2000. 10:1115-1125); sequence features (such as trans-splice and polyA sites). Sources of data: large-scale EST projects of Yuji Kohara (http://www.ddbj.nig.ac.jp/c-elegans/html/CE_INDEX.html); ORFeome cloning project (http://worfdb.dfci.harvard.edu); RST large-scale sequencing project (Genome Res. 2009. 19:2334-2342); IST library (Science. 2004. 303:540-3); RT-PCR EST set (Ewing B. Green P. 2010 Unpublished); UTRome EST data submission (UTRome v1 Mangone M. Piano F. 2009); TEC-RED data (PNAS 2004. 101:1650-1655); RNA Deep sequencing data (454 read clusters - Makedonka Mitreva, unpublished; Illumina sequence data, Genome Res. 2009. 19:657-66); Numerous data sets from the modENCODE project (Science. 2010. 330:1775-87); Individual C. elegans Nucleotide Database submissions; Personal communications with C. elegans researchers; Non-Coding gene structures below are derived using the following methods and data: ab initio prediction of tRNAs by tRNAscan-SE (Nucl. Acids. Res., 25, 955-964); integration and appraisal of miRNAs from miRBase (http://www.mirbase.org); integration and appraisal of RFAM predictions (rfam.sanger.ac.uk); 21U-RNAs (Cell. 2006. 127:1193-1207); modENCODE data (Science. 2010. 330:1775-87); manual curation of novel published ncRNAs from the literature. FEATURES Qualifiers source /organism="Caenorhabditis elegans" /chromosome="X" /strain="Bristol N2" /mol_type="genomic DNA" /db_xref="taxon:6239" protein /transl_table=1 /gene="daf-12" /locus_tag="CELE_F11A1.3" /standard_name="F11A1.3b" /note="Confirmed by transcript evidence" /db_xref="GOA:G5EFF5" /db_xref="InterPro:IPR000536" /db_xref="InterPro:IPR001628" /db_xref="InterPro:IPR013088" /db_xref="InterPro:IPR035500" /db_xref="UniProtKB/Swiss-Prot:G5EFF5" /db_xref="WormBase:WBGene00000908" intron_pos 23:1 (1/14) intron_pos 51:0 (2/14) intron_pos 92:0 (3/14) intron_pos 181:0 (4/14) intron_pos 197:0 (5/14) intron_pos 221:0 (6/14) intron_pos 253:0 (7/14) intron_pos 278:0 (8/14) intron_pos 310:2 (9/14) intron_pos 428:0 (10/14) intron_pos 488:0 (11/14) intron_pos 585:2 (12/14) intron_pos 639:2 (13/14) intron_pos 665:0 (14/14) BEGIN 1 MSTPDDPVIH SPPSIGAAPG MNGYHGSGVK LEESSGACGS PDDGLLDSSE ESRRRQKTCR 61 VCGDHATGYN FNVITCESCK AFFRRNALRP KEFKCPYSED CEINSVSRRF CQKCRLRKCF 121 TVGMKKEWIL NEEQLRRRKN SRLNNTGTCN KRSQPGNQQS PQGPNQQPHL SPHHPGVAIY 181 PPQPQRPLTI NPMDNQMMHH MQANRPNAMP QLISPPGAQP YPLTSPVGSS ASDSPPNRSL 241 TMMHNGEKSP DGYDPNIMAH RAPPPSFNNR PKMDSGQVVL STEEYKQLLS RIPGAQVPGL 301 MNEEEPINKR AAYNCNGHPM PAETTPPYSA PMSDMSLSRH NSTSSGTEKN HMTHSTVSAI 361 PGNSAQNHFD IASFGMGIVT ATGGGDAAEE MYKRMNMFYE NCIQSALDSP ENQEPKPQEA 421 MIPKEEYMTP THGFQYQSDP YQVPPAERNI NYQLNAAELK ALDAVREAFY GMDDPMEQGR 481 QMQSFLKANK TPADIMNIMD VTMRRFVKVA KGVPAFREVS QEGKFSLLKG GMIEMLTVRG 541 VTRYDASTNS FKTPTIKGQN VSVNVDDMFA KLNANAQAQK AKCLEFFGFF DEEIKKNELA 601 VYLVMLAVLF SVRSDPPMNE NDVRIVTERH NHFMSLLNRY LESLFGEQAR RIFERIPKAL 661 GLLNEIARNA GMLFMGTVRS GEAEELPGEF FKIK //