LOCUS       CAB5248301.1             261 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 27
            kDa antigen Cfp30B protein.
ACCESSION   LT708304-600
PROTEIN_ID  CAB5248301.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="cfp32"
                     /locus_tag="BQ2027_MB0592"
                     /note="Mb0592, TB27.3, len: 261 aa. Equivalent to Rv0577,
                     len: 261 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 261 aa overlap). TB27.3, conserved
                     hypothetical protein. Corresponds to O53774|CF30_MYCTU 27
                     KD ANTIGEN CFP30B from Mycobacterium tuberculosis culture
                     filtrate (260 aa), FASTA scores: opt: 1781, E(): 0,
                     (100.0% identity in 260 aa overlap). Also similar to
                     several hypothetical proteins and hydroxylases from
                     Steptomyces sp. e.g. T35032 probable hydroxylase from
                     Streptomyces coelicolor (263 aa); Q55078 orfA gene product
                     from Streptomyces sp. (275 aa), FASTA scores: E(): 1.5e-1
                     9, (38.6% identity in 264 aa overlap); D89734_1|P95754 DNA
                     for SgaA SGAA PROTEIN from Streptomyces griseus; and
                     SC9B10_20 from Streptomyces coelicolor (267 aa), FASTA
                     score: (38.9 identity in 252 aa overlap). Also similar to
                     Rv0911|MTCY21C12.05 from Mycobacterium tuberculosis (257
                     aa), FASTA scores: E(): 1.1e-20, (32.0% identity in 259 aa
                     overlap). Protein product from Mb0592 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb0592 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPKRSEYRQG TPNWVDLQTT DQSAAKKFYT SLFGWGYDDN PVPGGGGVYS MATLNGEAVA
       61 AIAPMPPGAP EGMPPIWNTY IAVDDVDAVV DKVVPGGGQV MMPAFDIGDA GRMSFITDPT
      121 GAAVGLWQAN RHIGATLVNE TGTLIWNELL TDKPDLALAF YEAVVGLTHS SMEIAAGQNY
      181 RVLKAGDAEV GGCMEPPMPG VPNHWHVYFA VDDADATAAK AAAAGGQVIA EPADIPSVGR
      241 FAVLSDPQGA IFSVLKPAPQ Q
//