LOCUS CAB5248298.1 380 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Capsule biosynthesis protein CapA protein. ACCESSION LT708304-597 PROTEIN_ID CAB5248298.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0589C" /note="Mb0589c, -, len: 380 aa. Equivalent to Rv0574c, len: 380 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 380 aa overlap). Conserved hypothetical protein, showing similarity with other hypothetical proteins and polyglutamate synthases (encapsulation proteins) e.g. AAK64444.1|AF377339_5|AF377339 polyglutamate synthase CapA from Myxococcus xanthus (405 aa); M24150|BACCAPABC_3|CapA polyglutamate synthase (encapsulation protein) from B.anthracis (411 aa), FASTA scores: opt: 261, E(): 4.3e-10, (25.8% identity in 287 aa overlap); etc. Mb0589c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MAGKPDVVTV LLGGDVMLGR GVDQILPHPG KPQLRERYMR DATGYVRLAE RVNGRIPLPV 61 DWRWPWGEAL AVLENTATDV CLINLETTIT ADGEFADRKP VCYRMHPDNV PALTALRPHV 121 CALANNHILD FGYQGLTDTV AALAGAGIQS VGAGADLLAA RRSALVTVGH ERRVIVGSVA 181 AESSGVPESW AARRDRPGVW LIRDPAQRDV ADDVAAQVLA DKRPGDIAIV SMHWGSNWGY 241 ATAPGDVAFA HRLIDAGIDM VHGHSSHHPR PIEIYRGKPI LYGCGDVVDD YEGIGGHESF 301 RSELRLLYLT VTDPASGNLI SLQMLPLRVS RMRLQRASQT DTEWLRNTIE RISRRFGIRV 361 VTRPDNLLEV VPAANLTSKE //