LOCUS       CAB5248280.1             378 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 mannosyltransfera
            se mgta protein.
ACCESSION   LT708304-579
PROTEIN_ID  CAB5248280.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="mgta"
                     /locus_tag="BQ2027_MB0572"
                     /note="Mb0572, pimB, len: 378 aa. Equivalent to Rv0557,
                     len: 378 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 378 aa overlap). pimB (alternate gene
                     name: mtfB), mannosyltransferase (EC 2.4.1.-) (see
                     citation below), similar to other various transferases
                     e.g. NP_243554.1|NC_002570
                     alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol
                     monomannoside transferase from Bacillus halodurans (381
                     aa); NP_249533.1|NC_002516 probable glycosyl transferase
                     from Pseudomonas aeruginosa (406 aa);
                     NP_419573.1|NC_002696 glycosyl transferase, group 1 family
                     protein, from Caulobacter crescentus (455 aa); etc. Also
                     similar to Q55598 hypothetical 44.9 kDa protein from
                     SYNECHOCYSTIS SP (409 aa), FASTA scores: opt: 703, E(): 0,
                     (33.9% identity in 378 aa overlap); GPI3_YEAST|P32363
                     n-acetylglucosaminyl-phosphatidylinositol biosynthetic
                     protein (452 aa), FASTA scores: opt: 230, E(): 1.1e-07,
                     (23.5% identity in 328 aa overlap). Mb0572 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MCGVRVAIVA ESFLPQVNGV SNSVVKVLEH LRRTGHEALV IAPDTPPGED RAERLHDGVR
       61 VHRVPSRMFP KVTTLPLGVP TFRMLRALRG FDPDVVHLAS PALLGYGGLH AARRLGVPTV
      121 AVYQTDVPGF ASSYGIPMTA RAAWAWFRHL HRLADRTLAP STATMESLIA QGIPRVHRWA
      181 RGVDVQRFAP SARNEVLRRR WSPDGKPIVG FVGRLAPEKH VDRLTGLAAS GAVRLVIVGD
      241 GIDRARLQSA MPTAVFTGAR YGKELAEAYA SMDVFVHSGE HETFCQVVQE ALASGLPVIA
      301 PDAGGPRDLI TPHRTGLLLP VGEFEHRLPD AVAHLVHERQ RYALAARRSV LGRSWPVVCD
      361 ELLGHYEAVR GRRTTQAA
//