LOCUS       CAB5248270.1             314 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 naphthoate
            synthase menb (dihydroxynaphthoic acid synthetase) (dhna
            synthetase) protein.
ACCESSION   LT708304-569
PROTEIN_ID  CAB5248270.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="menB"
                     /locus_tag="BQ2027_MB0562C"
                     /note="Mb0562c, menB, len: 314 aa. Equivalent to Rv0548c,
                     len: 314 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 314 aa overlap). Probable menB,
                     naphthoate synthase (dihydroxynaphthonic acid synthase)
                     (EC 4.1.3.36), equivalent to NP_302473.1|NC_002677
                     naphthoate synthase from Mycobacterium leprae (300 aa).
                     Also similar to others e.g. MENB_ECOLI|P27290 naphthoate
                     synthase from Escherichia coli (285 aa), FASTA scores:
                     opt: 599, E(): 9.3e-33, (48.1 identity in 285 aa overlap);
                     etc. BELONGS TO THE ENOYL-COA HYDRATASE/ISOMERASE FAMILY.
                     Protein product from Mb0562c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0562c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MVAPAGEQGR SSTALSDNPF DAKAWRLVDG FDDLTDITYH RHVDDATVRV AFNRPEVRNA
       61 FRPHTVDELY RVLDHARMSP DVGVVLLTGN GPSPKDGGWA FCSGGDQRIR GRSGYQYASG
      121 DTADTVDVAR AGRLHILEVQ RLIRFMPKVV ICLVNGWAAG GGHSLHVVCD LTLASREYAR
      181 FKQTDADVGS FDGGYGSAYL ARQVGQKFAR EIFFLGRTYT AEQMHQMGAV NAVAEHAELE
      241 TVGLQWAAEI NAKSPQAQRM LKFAFNLLDD GLVGQQLFAG EATRLAYMTD EAVEGRDAFL
      301 QKRPPDWSPF PRYF
//