LOCUS       CAB5248263.1             449 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-562
PROTEIN_ID  CAB5248263.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0555C"
                     /note="Mb0555c, -, len: 449 aa. Equivalent to Rv0541c,
                     len: 449 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 449 aa overlap). Probable conserved
                     integral membrane protein, highly similar (except first 40
                     residues) to CAB76994.1|AL159178 putative integral
                     membrane protein from Streptomyces coelicolor (456 aa).
                     Also some similarity to Q13724|GCS1_HUMAN
                     MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE (834 aa), FASTA
                     scores: opt: 150, E(): 0.013, (27.1% identity in 339 aa
                     overlap). Contains PS00041 Bacterial regulatory proteins,
                     araC family signature. Mb0555c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MRIGRREGLA VAIGFVLVGA AFVLPRLNLG IKPRSDIGLE RFATRAGAAP IFGYWDAHVG
       61 WGTAPAVLTA VAVVAWGPVV AHRLPWRVLT LSTWATAAAW AFSLAMIDGW QRGFAGRLTT
      121 RDEYLWQVPG IADIPATLRT FTSRILDFQP NSWVTHVSGH PPGALLTFVW LDRIGLRGGG
      181 WAGLVCLLVG SSAAAAVLIA VRVLASEQMA RRTAPFVAVA PTAIWVAVSA DGYFAGVAAW
      241 GIALLAVAVH GATRFPALVA AGAGLLLGWG VFLNYGLVLI VLPGMAVLAA ADWRPVLRAL
      301 GPAVLAALVV AVSFAVAGFS WFDGYTLVQQ RYWQGIAKDR PFGYWSWANL ACVVCAIGLG
      361 SVAGLSRVFD RAAISRRSGC HLLLLAVLAA IALADLSMLS KAETERIWLP FTIWLTAAPA
      421 LLPPRSHRLW LAVNAAGALL LNSIIFTNW
//