LOCUS CAB5248263.1 449 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN protein. ACCESSION LT708304-562 PROTEIN_ID CAB5248263.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0555C" /note="Mb0555c, -, len: 449 aa. Equivalent to Rv0541c, len: 449 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 449 aa overlap). Probable conserved integral membrane protein, highly similar (except first 40 residues) to CAB76994.1|AL159178 putative integral membrane protein from Streptomyces coelicolor (456 aa). Also some similarity to Q13724|GCS1_HUMAN MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE (834 aa), FASTA scores: opt: 150, E(): 0.013, (27.1% identity in 339 aa overlap). Contains PS00041 Bacterial regulatory proteins, araC family signature. Mb0555c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MRIGRREGLA VAIGFVLVGA AFVLPRLNLG IKPRSDIGLE RFATRAGAAP IFGYWDAHVG 61 WGTAPAVLTA VAVVAWGPVV AHRLPWRVLT LSTWATAAAW AFSLAMIDGW QRGFAGRLTT 121 RDEYLWQVPG IADIPATLRT FTSRILDFQP NSWVTHVSGH PPGALLTFVW LDRIGLRGGG 181 WAGLVCLLVG SSAAAAVLIA VRVLASEQMA RRTAPFVAVA PTAIWVAVSA DGYFAGVAAW 241 GIALLAVAVH GATRFPALVA AGAGLLLGWG VFLNYGLVLI VLPGMAVLAA ADWRPVLRAL 301 GPAVLAALVV AVSFAVAGFS WFDGYTLVQQ RYWQGIAKDR PFGYWSWANL ACVVCAIGLG 361 SVAGLSRVFD RAAISRRSGC HLLLLAVLAA IALADLSMLS KAETERIWLP FTIWLTAAPA 421 LLPPRSHRLW LAVNAAGALL LNSIIFTNW //