LOCUS       CAB5248248.1             529 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED TRANSMEMBRANE PROTEIN protein.
ACCESSION   LT708304-547
PROTEIN_ID  CAB5248248.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0541"
                     /note="Mb0541, -, len: 529 aa. Equivalent to Rv0528, len:
                     529 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 529 aa overlap). Probable conserved
                     transmembrane protein, equivalent (shorter 14 aa in
                     N-terminus) to CAC31926.1|AL583925 conserved membrane
                     protein from Mycobacterium leprae (542 aa). Also highly
                     similar to Q49817|B2168_C2_237|S72902 hypothetical protein
                     from Mycobacterium leprae (364 aa), FASTA scores: opt:
                     1846, E(): 0, (81.1% identity in 338 aa overlap); and
                     Q49811|B2168_C1_194|S72891 hypothetical protein from
                     Mycobacterium leprae (106 aa), FASTA scores: opt: 506,
                     E(): 3.8e-26, (73.6% identity in 106 aa overlap). Also
                     highly similar to CAC08381.1|AL392176 putative integral
                     membrane protein from Streptomyces coelicolor (574 aa).
                     Protein product from Mb0541 detected using SWATH mass
                     spectrometry. Mb0541 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MWRSLTSMGT ALVLLFLLAL AAIPGALLPQ RGLNAAKVDD YLAAHPLIGP WLDELQAFDV
       61 FSSFWFTAIY VLLFVSLVGC LAPRTIEHAR SLRATPVAAP RNLARLPKHA HARLAGEPAA
      121 LAATITGRLR GWRSITRQQG DSVEVSAEKG YLREFGNLVF HFALLGLLVA VAVGKLFGYE
      181 GNVIVIADGG PGFCSASPAA FDSFRAGNTV DGTSLHPICV RVNNFQAHYL PSGQATSFAA
      241 DIDYQADPAT ADLIANSWRP YRLQVNHPLR VGGDRVYLQG HGYAPTFTVT FPDGQTRTST
      301 VQWRPDNPQT LLSAGVVRID PPAGSYPNPD ERRKHQIAIQ GLLAPTEQLD GTLLSSRFPA
      361 LNAPAVAIDI YRGDTGLDSG RPQSLFTLDH RLIEQGRLVK EKRVNLRAGQ QVRIDQGPAA
      421 GTVVRFDGAV PFVNLQVSHD PGQSWVLVFA ITMMAGLLVS LLVRRRRVWA RITPTTAGTV
      481 NVELGGLTRT DNSGWGAEFE RLTGRLLAGF EARSPDMAEA AAGTGRDVD
//