LOCUS       CAB5248245.1             202 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Hypothetical,
            related to broad specificity phosphatases COG0406 protein.
ACCESSION   LT708304-544
PROTEIN_ID  CAB5248245.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0538"
                     /note="Mb0538, -, len: 202 aa. Equivalent to Rv0525, len:
                     202 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 202 aa overlap). Conserved
                     hypothetical protein, equivalent to
                     Q49821|B2168_C3_276|S72912 hypothetical protein from
                     Mycobacterium leprae (202 aa), FASTA scores: opt: 1151,
                     E(): 0, (82.5% identity in 200 aa overlap). Also highly
                     similar to CAC08377.1|AL392176 putative phosphoglycerate
                     mutase from Streptomyces coelicolor (233 aa); and similar
                     to SLL0395|Q55734 hypothetical 23.8 kDa protein from
                     SYNECHOCYSTIS SP. (212 aa), FASTA scores: opt: 207, E():
                     5.1e-07, (28.2% identity in 195 aa overlap). Also some
                     similarity to Rv2228c|Y019_MYCTU|Q10512|cy427.09
                     hypothetical 39.2 kd protein from Mycobacterium
                     tuberculosis (364 aa), FASTA scores: opt: 236, E():
                     1.1e-08, (34.3% identity in 198 aa overlap). Protein
                     product from Mb0538 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0538 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPEETQVHVV RHGEVHNPTG ILYGRLPGFH LSATGAAQAA AVADALADRD IVAVIASPLQ
       61 RAQETAAPIA ARHDLAVETD PDLIESANFF EGRRVGPGDG AWRDPRVWWQ LRNPFTPSWG
      121 EPYVDIAARM TTAVDKARVR GAGHEVVCVS HQLPVWTLRL YLTGKRLWHD PRRRDCALAS
      181 VTSLIYDGDR LVDVVYSQPA AL
//