LOCUS       CAB5248212.1             242 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY)
            protein.
ACCESSION   LT708304-511
PROTEIN_ID  CAB5248212.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0505"
                     /note="Mb0505, -, len: 242 aa. Equivalent to Rv0494, len:
                     242 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 242 aa overlap). Probable
                     transcriptional regulator, GntR family, with C-terminal
                     part highly similar to S72893|B2168_C2_205 hypothetical
                     protein from Mycobacterium leprae (105 aa). Also similar
                     to other transcription regulators e.g. PDHR_ECOLI|P06957
                     pyruvate dehydrogenase complex repressor PDHR or GENA from
                     Escherichia coli (254 aa), FASTA scores: opt: 284, E():
                     1.2e-11, (32.6% identity in 224 aa overlap); etc. Contains
                     PS00043 Bacterial regulatory proteins, gntR family
                     signature, and probable helix-turn helix motif from aa
                     50-71 (Score 1229, +3.37 SD)."
BEGIN
        1 MVEPMNQSSV FQPPDRQRVD ERIATTIADA ILDGVFPPGS TLPPERDLAE RLGVNRTSLR
       61 QGLARLQQMG LIEVRHGSGS VVRDPEGLTH PAVVEALVRK LGPDFLVELL EIRAALGPLI
      121 GRLAAARSTP EDAEALCAAL EVVQQADTAA ARQAADLAYF RVLIHSTRNR ALGLLYRWVE
      181 HAFGGREHAL TGAYDDADPV LTDLRAINGA VLAGDPAAAA ATVEAYLNAS ALRMVKSYRD
      241 RA
//