LOCUS       CAB5248209.1             629 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            OXIDOREDUCTASE GMC-TYPE protein.
ACCESSION   LT708304-508
PROTEIN_ID  CAB5248209.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0502C"
                     /note="Mb0502c, -, len: 629 aa. Equivalent to Rv0492c,
                     len: 629 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 629 aa overlap). Probable
                     oxidoreductase GMC type (EC 1.-.-.-), similar to others
                     except in N-terminus e.g. P55582|AE000087_5|Y4NJ_RHISN
                     HYPOTHETICAL GMC-TYPE OXIDOREDUCTASE from Rhizobium sp.
                     (505 aa), FASTA scores: opt: 873, E():0, (34.3% identity
                     in 502 aa overlap); YTH2_RHOER|P46371 HYPOTHETICAL 53.0 kd
                     GMC-TYPE OXIDOREDUCTASE from Rhodococcus erythropolis (493
                     aa), FASTA score: (25.7% identity in 521 aa overlap);
                     YTH2_RHOSO|P46371 hypothetical 53.0 kd gmc-type
                     oxidoreductase from Rhodococcus erythropolis (493 aa),
                     FASTA score: (25.7% identity in 521 aa overlap);
                     NP_085596.1|NC_002679 probable oxidoreductase from
                     Mesorhizobium loti (507 aa); NP_285451.1|NC_001264 GMC
                     oxidoreductase from Deinococcus radiodurans (722 aa);
                     NP_249055.1|NC_002516 probable oxidoreductase from
                     Pseudomonas aeruginosa (531 aa); etc. Contains PS00198
                     4Fe-4S ferredoxins, iron-sulfur binding region signature,
                     and PS00624 GMC oxidoreductases signature 2. BELONGS TO
                     THE GMC OXIDOREDUCTASES FAMILY. COFACTOR: FAD (BY
                     SIMILARITY). Note that start changed since first
                     submission (previously 684 aa). Protein product from
                     Mb0502c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0502c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MSRLADRAKS YPLASFGAAL LPPELGGPLP AQFVQRVDRY VTRLPATSRF AVRAGLASLA
       61 AASYLTTGRS LPRLHPDERA RVLHRIAALS PEVAAAVEGL KAIVLLANGA DTYAHELLAR
      121 AQEHDAARPD AELTVILSAD SPSVTRADAV VVGSGAGGAM VARTLARAGL DVVVLEEGRR
      181 WTVEEFRSTH PVDRYAGLYR GAGATVALGR PAVVLPMGRA VGGTTVVNSG TCFRPSLAVQ
      241 RRWRDEFGLG LADPDQLGRR LDDAEQTLRV APVPLEIMGR NGRLLLQAAK SLGWRAAPIP
      301 RNAPGCRGCC QCAIGCPSNA KFGVHLNALP QACAAGARII SWARVERILH RAGRAYGVRA
      361 RRPDGTTLDV LADAVVVAAG ATETPGLLRR SGLGGHPRLG HNLALHPATM LAGLFDDDVF
      421 AWRGVLQSAA VHEFHESDGV LIEATSTPPG MGSMVFPGYG AELLRWLDRA PQIATFGAMV
      481 ADRGVGTVRS VRGETVVRYD IAPGEIAKLR VALQAIGRLF FAAGAVEVLT GIPGAPPMRS
      541 LPELQDVLRR ANPRSLHLAA FHPTGTAAAG ADEQLCPVDA TGRLRGVEGV WVADASILPS
      601 CPEVNPQLSI MAMALAVADQ TVAKVVGVR
//