LOCUS       CAB5248206.1             249 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE)
            (PGAM) (BPG-DEPENDENT PGAM) protein.
ACCESSION   LT708304-505
PROTEIN_ID  CAB5248206.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="gpm1"
                     /locus_tag="BQ2027_MB0499"
                     /note="Mb0499, gpm1, len: 249 aa. Equivalent to Rv0489,
                     len: 249 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 249 aa overlap). Probable gpm1,
                     phosphoglycerate mutase 1 (EC 5.4.2.1), equivalent to
                     P53531|PMGY_MYCLE PHOSPHOGLYCERATE MUTASE from
                     Mycobacterium leprae (247 aa). Also highly similar to
                     others e.g. PMG1_ECOLI|P31217 (249 aa), FASTA scores: opt:
                     805, E(): 0, (51.4% identity in 245 aa overlap); etc.
                     Contains PS00175 Phosphoglycerate mutase family
                     phosphohistidine signature, and PS00017 ATP/GTP-binding
                     site motif A (P-loop). BELONGS TO THE PHOSPHOGLYCERATE
                     MUTASE FAMILY. Note that previously known as gpm. Protein
                     product from Mb0499 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0499 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MANTGSLVLL RHGESDWNAL NLFTGWVDVG LTDKGQAEAV RSGELIAEHD LLPDVLYTSL
       61 LRRAITTAHL ALDSADRLWI PVRRSWRLNE RHYGALQGLD KAETKARYGE EQFMAWRRSY
      121 DTPPPPIERG SQFSQDADPR YADIGGGPLT ECLADVVARF LPYFTDVIVG DLRVGKTVLI
      181 VAHGNSLRAL VKHLDQMSDD EIVGLNIPTG IPLRYDLDSA MRPLVRGGTY LDPEAAAAGA
      241 AAVAGQGRG
//