LOCUS       CAB5248196.1             348 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED MEMBRANE PROTEIN protein.
ACCESSION   LT708304-495
PROTEIN_ID  CAB5248196.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0489C"
                     /note="Mb0489c, -, len: 348 aa. Equivalent to Rv0479c,
                     len: 348 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 348 aa overlap). Probable conserved
                     membrane protein, equivalent to CAC31967.1|AL583925
                     possible secreted protein from Mycobacterium leprae (254
                     aa); and C-terminus highly similar to
                     AAF74996.1|AF143402_1|AF143402 putative multicopper
                     oxidase from Mycobacterium avium (149 aa). Contains
                     hydrophobic domain in centre of protein. Protein product
                     from Mb0489c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0489c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MTNPQGPPND PSPWARPGDQ GPLARPPASS EASTGRLRPG EPAGHIQEPV SPPTQPEQQP
       61 QTEHLAASHA HTRRSGRQAA HQAWDPTGLL AAQEEEPAAV KTKRRARRDP LTVFLVLIIV
      121 FSLVLAGLIG GELYARHVAN SKVAQAVACV VKDQATASFG VAPLLLWQVA TRHFTNISVE
      181 TAGNQIRDAK GMQIKLTIQN VRLKNTPNSR GTIGALDATI TWSSEGIKES VQNAIPILGA
      241 FVTSSVVTHP ADGTVELKGL LNNITAKPIV AGKGLELQII NFNTLGFSLP KETVQSTLNE
      301 FTSSLTKNYP LGIHADSVQV TSTGVVSRFS TRDAAIPTGI QNPCFSHI
//