LOCUS CAB5248196.1 348 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED MEMBRANE PROTEIN protein. ACCESSION LT708304-495 PROTEIN_ID CAB5248196.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0489C" /note="Mb0489c, -, len: 348 aa. Equivalent to Rv0479c, len: 348 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 348 aa overlap). Probable conserved membrane protein, equivalent to CAC31967.1|AL583925 possible secreted protein from Mycobacterium leprae (254 aa); and C-terminus highly similar to AAF74996.1|AF143402_1|AF143402 putative multicopper oxidase from Mycobacterium avium (149 aa). Contains hydrophobic domain in centre of protein. Protein product from Mb0489c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0489c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MTNPQGPPND PSPWARPGDQ GPLARPPASS EASTGRLRPG EPAGHIQEPV SPPTQPEQQP 61 QTEHLAASHA HTRRSGRQAA HQAWDPTGLL AAQEEEPAAV KTKRRARRDP LTVFLVLIIV 121 FSLVLAGLIG GELYARHVAN SKVAQAVACV VKDQATASFG VAPLLLWQVA TRHFTNISVE 181 TAGNQIRDAK GMQIKLTIQN VRLKNTPNSR GTIGALDATI TWSSEGIKES VQNAIPILGA 241 FVTSSVVTHP ADGTVELKGL LNNITAKPIV AGKGLELQII NFNTLGFSLP KETVQSTLNE 301 FTSSLTKNYP LGIHADSVQV TSTGVVSRFS TRDAAIPTGI QNPCFSHI //