LOCUS       CAB5248173.1             676 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PEPTIDASE protein.
ACCESSION   LT708304-472
PROTEIN_ID  CAB5248173.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0466C"
                     /note="Mb0466c, -, len: 676 aa. Equivalent to Rv0457c,
                     len: 673 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 673 aa overlap). Probable peptidase
                     (EC 3.4.-.-), similar to many e.g.
                     NP_102851.1|14022026|BAB48637.1 probable endopeptidase
                     from Mesorhizobium loti (687 aa); Y4NA_RHISN|P55577
                     probable peptidase (EC 3.4.21.-) (726 aa), FASTA scores:
                     opt: 1126, E(): 0, (40.9% identity in 491 aa overlap).
                     Also similar to Mycobacterium tuberculosis protein
                     MTCY369.26 FASTA score: (33.8% identity in 299 aa
                     overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     bovis, a possible RBS upstream leads to an earlier start
                     resulting in a slightly longer product compared to its
                     homolog in Mycobacterium tuberculosis strain H37Rv (676 aa
                     versus 673 aa). Protein product from Mb0466c detected
                     using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0466c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MASMTFEPAP DGADPYLWLE DVTGAEALDW VRARNKPTTA AFCDAEFERM RVEALEVLDT
       61 DARIPYVNRR GNYLYNFWRD AANPRGLWRR TTLDSYRTDS PGWDVLIDVD ELGRADDQKW
      121 VWGGAGVIEP DYTRALIGLS PGGSDASIVR EFDMLTREFV EDGFQLPPAK SQITWEDPDT
      181 VLLGTDFGGD SLTTSGYPRV IKRWRRGKPL ADAETIFEGA GTDVRVNASA DRTPGFERTL
      241 LGRALDFWNE EVYELRGSEL IRIEAPTDAS VSIHRDWLLI ELRTDWTVAT TRYTAGSLLA
      301 AEYDEFLAGS AELQVVFEPD EHTALYQYAW TRDRLLIVTL ADVASRVEIA TPGSWRREPL
      361 SGIPAATNTV IVSADSHGDE FFLDSSGFDT PSRLMRGTDD GRLAEIKSAP AFFDAENMAV
      421 TQYFATSDDG TSIPYFVVRR TDADNPGPTL LNGYGGFETS RTPTYDGVLG RLWLARGGTY
      481 ALANIRGGGE YGPGWHTQAM REGRDKVAQD FAAVATDLVT RGITTAEQLG ARGGSNGGLL
      541 MGIMLTGYPE KFGALVCDVP LLDMKRYHLL LAGASWMAEY GDPDNPDDWK FISEYSPYQN
      601 ISANRKYPPV LMTTSTRDDR VHPGHARKMT AALQAAGHPV WYYENIEGGH AGAADNAQIA
      661 FKSALSFAFL WRMLAG
//