LOCUS CAB5248158.1 232 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 anti- sigma factor rska (regulator of sigma k) protein. ACCESSION LT708304-457 PROTEIN_ID CAB5248158.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="rska" /locus_tag="BQ2027_MB0452C" /note="Mb0452c, -, len: 232 aa. Equivalent to Rv0444c, len: 232 aa, from Mycobacterium tuberculosis strain H37Rv, (99.1% identity in 232 aa overlap). Conserved hypothetical protein; C-terminus similar to P12752|Y24K_STRGR HYPOTHETICAL 24.7 KD PROTEIN from Streptomyces griseus (238 aa), FASTA scores: opt: 207, E(): 2.2e-05, (32.9% identity in 158 aa overlap). Protein product from Mb0452c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0452c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MTEHTDFELL ELATPYALNA VSDDERADID RRVAAAPSPV AAAFNDEVRA VRETMAVVSA 61 ATTAEPPAHL RTAILDATKP EVRRQSRWRT AAFASAAAIA VGLGAFDLGV LTRPSPPPTV 121 AEQVLTAPDV RTVSRPLGAG TATVVFSRDR NTGLLVMNNV APPSRGTVYQ MWLLGGAKGP 181 RSAETMGTAA VTPSTTATLT DLGASTALAF TVEPGTGSPQ PTGTILAELP LG //