LOCUS       CAB5248151.1             231 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            PHOSPHATIDYLSERINE DECARBOXYLASE PSD (PS DECARBOXYLASE)
            protein.
ACCESSION   LT708304-450
PROTEIN_ID  CAB5248151.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="psd"
                     /locus_tag="BQ2027_MB0445C"
                     /note="Mb0445c, psd, len: 231 aa. Equivalent to Rv0437c,
                     len: 231 aa (start uncertain), from Mycobacterium
                     tuberculosis strain H37Rv, (100.0% identity in 231 aa
                     overlap). Possible psd, phosphatidylserine decarboxylase
                     (EC 4.1.1.65), equivalent to CAC29819.1|AL583918 conserved
                     hypothetical protein from Mycobacterium leprae (243 aa);
                     and highly similar to
                     MLCB1450.11|T44729|4154044|CAA22695.1|AL035159
                     hypothetical protein from Mycobacterium leprae (202 aa),
                     FASTA score: (74.6% identity in 197 aa overlap). Also
                     similar to other phosphatidylserine decarboxylases e.g.
                     NP_108058.1|14027249|BAB54203.1|AP003012
                     phosphatidylserine decarboxylase from Mesorhizobium loti
                     (232 aa); AAK86872|g15156090|AGR_C_1963 phosphatidylserine
                     decarboxylase from Agrobacterium tumefaciens (244 aa);
                     AAG12422.1|AY005137|Psd phosphatidylserine decarboxylase
                     from Chlorobium tepidum (216 aa); etc. Protein product
                     from Mb0445c detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0445c found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MARRPRPDGP QHLLALVRSA VPPVHPAGRP FIAAGLAIAA VGHRYRWLRG TGLLAAAACA
       61 GFFRHPQRVP PTRPAAIVAP ADGVICAIDS AAPPAELSMG DTPLPRVSIF LSILDAHVQR
      121 APVSGEVIAV QHRPGRFGSA DLPEASDDNE RTSVRIRMPN GAEVVAVQIA GLVARRIVCD
      181 AHVGDKLAIG DTYGLIRFGS RLDTYLPAGA EPIVNVGQRA VAGETVLAEC R
//