LOCUS       CAB5248149.1             728 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE
            CONSERVED ATPASE protein.
ACCESSION   LT708304-448
PROTEIN_ID  CAB5248149.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0443C"
                     /note="Mb0443c, -, len: 728 aa. Equivalent to Rv0435c,
                     len: 728 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 728 aa overlap). Putative conserved
                     ATPase (EC 3.6.1.-), similar to others e.g.
                     SAV_SULAC|Q07590 sav protein involved in cell division
                     from sulfolobus acidocaldarius (780 aa), FASTA scores:
                     opt: 897, E(): 0, (34.5% identity in 693 aa overlap);
                     NP_148637.1|7435761|B72479 transitional endoplasmic
                     reticulum ATPase from Aeropyrum pernix (699 aa); etc. Also
                     similar to Rv3610c and Rv2115c from Mycobacterium
                     tuberculosis. Contains PS00017 ATP/GTP-binding site motif
                     A (P-loop), and PS00674 AAA-protein family signature.
                     Protein product from Mb0443c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0443c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MTHPDPARQL TLTARLNTSA VDSRRGVVRL HPNAIAALGI REWDAVSLTG SRTTAAVAGL
       61 AAADTAVGTV LLDDVTLSNA GLREGTEVIV SPVTVYGARS VTLSGSTLAT QSVPPVTLRQ
      121 ALLGKVMTVG DAVSLLPRDL GPGTSTSAAS RALAAAVGIS WTSELLTVTG VDPDGPVSVQ
      181 PNSLVTWGAG VPAAMGTSTA GQVSISSPEI QIEELKGAQP QAAKLTEWLK LALDEPHLLQ
      241 TLGAGTNLGV LVSGPAGVGK ATLVRAVCDG RRLVTLDGPE IGALAAGDRV KAVASAVQAV
      301 RHEGGVLLIT DADALLPAAA EPVASLILSE LRTAVATAGV VLIATSARPD QLDARLRSPE
      361 LCDRELGLPL PDAATRKSLL EALLNPVPTG DLNLDEIASR TPGFVVADLA ALVREAALRA
      421 ASRASADGRP PMLHQDDLLG ALTVIRPLSR SASDEVTVGD VTLDDVGDMA AAKQALTEAV
      481 LWPLQHPDTF ARLGVEPPRG VLLYGPPGCG KTFVVRALAS TGQLSVHAVK GSELMDKWVG
      541 SSEKAVRELF RRARDSAPSL VFLDELDALA PRRGQSFDSG VSDRVVAALL TELDGIDPLR
      601 DVVMLGATNR PDLIDPALLR PGRLERLVFV EPPDAAARRE ILRTAGKSIP LSSDVDLDEV
      661 AAGLDGYSAA DCVALLREAA LTAMRRSIDA ANVTAADLAT ARETVRASLD PLQVASLRKF
      721 GTKGDLRS
//