LOCUS CAB5248145.1 164 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PUTATIVE TUBERCULIN RELATED PEPTIDE protein. ACCESSION LT708304-444 PROTEIN_ID CAB5248145.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0439" /note="Mb0439, -, len: 164 aa. Equivalent to Rv0431, len: 164 aa, from Mycobacterium tuberculosis strain H37Rv, (98.8% identity in 164 aa overlap). Putative tuberculin related peptide; almost identical to D00815|MSGAT103_1 AT103 from Mycobacterium tuberculosis (172 aa), FASTA score: (99.4% identity in 163 aa overlap). Highly similar to to CAC30881.1|AL583923 tuberculin related peptide (AT103) from Mycobacterium leprae (167 aa). Some similarity to G550415|HRPC (282 aa), FASTA scores: opt: 120, E(): 0.36, (33.3% identity in 111 aa overlap). Potential transmembrane domain at aa 19-37. Protein product from Mb0439 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0439 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MLVTVGSMNE RVPDSSGLPL RAMVMVLLFL GVVFLLLGWQ ALGSSPNSED DSSAISTMTT 61 TTAAPTSTSV KPAAPRAEVR VYNISGAEGA AARTADRLKA AGFTVTDVGN LSLPDVAATT 121 VYYTEVEGER ATADAVGRTL GAAVELRLPE LSDQPPGVIV VVTG //