LOCUS       CAB5248123.1             385 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            ACETATE KINASE ACKA (ACETOKINASE) protein.
ACCESSION   LT708304-422
PROTEIN_ID  CAB5248123.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="ackA"
                     /locus_tag="BQ2027_MB0417"
                     /note="Mb0417, ackA, len: 385 aa. Equivalent to Rv0409,
                     len: 385 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 385 aa overlap). Probable ackA,
                     acetate kinase (EC 2.7.2.1), highly similar to others e.g.
                     ACKA_BACSU|P37877 acetate kinase from Bacillus subtilis
                     (395 aa), FASTA scores: opt: 974, E(): 0, (43.5% identity
                     in 393 aa overlap); etc. Contains PS01075 Acetate and
                     butyrate kinases family signature 1, PS00758 ArgE / dapE /
                     ACY1/ CPG2 / yscS family signature 1. BELONGS TO THE
                     ACETOKINASE FAMILY. Protein product from Mb0417 detected
                     using SWATH mass spectrometry. Mb0417 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MSSTVLVINS GSSSLKFQLV EPVAGMSRAA GIVERIGERS SPVADHAQAL HRAFKMLAED
       61 GIDLQTCGLV AVGHRVVHGG TEFHQPTLLD DTVIGKLEEL SALAPLHNPP AVLGIKVARR
      121 LLANVAHVAV FDTAFFHDLP PAAATYAIDR DVADRWHIRR YGFHGTSHQY VSERAAAFLG
      181 RPLDGLNQIV LHLGNGASAS AIARGRPVET SMGLTPLEGL VMGTRSGDLD PGVISYLWRT
      241 ARMGVEDIES MLNHRSGMLG LAGERDFRRL RLVIETGDRS AQLAYEVFIH RLRKYLGAYL
      301 AVLGHTDVVS FTAGIGENDA AVRRDALAGL QGLGIALDQD RNLGPGHGAR RISSDDSPIA
      361 VLVVPTNEEL AIARDCLRVL GGRRA
//