LOCUS       CAB5248097.1             390 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            MONOOXYGENASE protein.
ACCESSION   LT708304-396
PROTEIN_ID  CAB5248097.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0392"
                     /note="Mb0392, -, len: 390 aa. Equivalent to Rv0385, len:
                     390 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 390 aa overlap). Probable
                     monooxygenase (EC 1.-.-.-), similar to
                     T37003|5738846|CAB52917.1|AL109949 probable
                     flavohemoprotein from Streptomyces coelicolor (435 aa);
                     and similar in part (C-termini) to various monooxygenases
                     e.g. P19734|DMPP_PSESP|94993|F37831 PHENOL HYDROXYLASE P5
                     PROTEIN (PHENOL 2-MONOOXYGENASE P5 COMPONENT) (EC
                     1.14.13.7) from Pseudomonas putida (353 aa), FASTA scores:
                     opt: 363, E(): 4.2e-16, (31.8% identity in 255 aa
                     overlap); S47292|2120861|pir|S70085 phenol 2-monooxygenase
                     (EC 1.14.13.7) chain mopP from Acinetobacter calcoaceticus
                     (350 aa); P21394|XYLA_PSEPU|94933|B37316 XYLENE
                     MONOOXYGENASE ELECTRON TRANSFER COMPONENT (EC 1.18.1.3)
                     [INCLUDES: FERREDOXIN; FERREDOXIN--NAD(+) REDUCTASE] from
                     Pseudomonas putida plasmid pWW0 (350 aa);
                     AAC38360.1|AF043544|NtnMA|ntnA reductase component of
                     4-nitrotoluene monooxygenase from Pseudomonas sp. (328
                     aa); etc. Protein product from Mb0392 detected using SWATH
                     mass spectrometry. Mb0392 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MGLEDRDALR VLQNAFKLDD PELVRRFYAH WFALDASVRD LFPPDMGAQR AAFGQALHWV
       61 YGELVAQRAE EPVAFLAQLG RDHRKYGVLP TQYDTLRRAL YTTLRDYLGH PSRGAWTDAV
      121 DEAAGQSLNL IIGVMSGAAD ADDAPAWWDG TVVEHIRVSR DLAVARLQLD RPLHYYPGQY
      181 VNVHVPQCPR RWRYLSPAIP ADPNGRIEFH VRVVPGGLVS NAIVGETRPG DRWRLSGPHG
      241 AFRVDRDGGD VLMVAGSTGL APLRALIIDL SRFAVNPRVH LFFGARYACE LYDLPTLWQI
      301 AAHNPWLSVS PVSEYNGDPA WAADYPDVSA PRGLHVRQTG RLPDVVSRYG GWGDRQILIC
      361 GGPAMVRATK AALIAKGAPP ERIQHDPLSR
//