LOCUS       CAB5248092.1             183 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            RNA METHYLTRANSFERASE (RNA METHYLASE) protein.
ACCESSION   LT708304-391
PROTEIN_ID  CAB5248092.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0387C"
                     /note="Mb0387c, -, len: 183 aa. Equivalent to Rv0380c,
                     len: 183 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 183 aa overlap). Possible RNA
                     methyltransferase (EC 2.1.1.-), equivalent to
                     CAC32002.1|AL583925 possible RNA methyltransferase from
                     Mycobacterium leprae (182 aa). Also some similarity with
                     others methyltransferases e.g.
                     P19396|TRMH_ECOLI|78514|JV0043 TRNA
                     (GUANOSINE-2'-O-)-METHYLTRANSFERASE (TRNA
                     METHYLTRANSFERASE) from Escherichia coli (229 aa), FASTA
                     scores: opt: 227, E(): 1.4e-09, (28.9% identity in 166 aa
                     overlap). Also similar to Rv0881, Rv3579c, Rv1644 from
                     Mycobacterium tuberculosis. Protein product from Mb0387c
                     detected using SWATH mass spectrometry. Mb0387c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MLLRDGDARN VVDAYRYWTR EAIIADIDTR RHPLHVAIEN FGHDANIGSV VRTANAFAVH
       61 TVHIVGRRRW NRRGAMVTDR YQRLCHHDST TGLLEFAAGA GLTVVAVDNV PGAARLEQTA
      121 LPRECLLLFG QEGPGITDDA RAGAAVTVSI AQFGSTRSIN AGVAAGIAMH AWIRQHADLG
      181 RAW
//