LOCUS       CAB5248091.1              71 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            PROTEIN TRANSPORT PROTEIN SECE2 protein.
ACCESSION   LT708304-390
PROTEIN_ID  CAB5248091.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="secE2"
                     /locus_tag="BQ2027_MB0386"
                     /note="Mb0386, secE2, len: 71 aa. Equivalent to Rv0379,
                     len: 71 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 71 aa overlap). Possible secE2,
                     protein transport protein, showing similarity with
                     P27340|S61G_SULSO|SECE PREPROTEIN TRANSLOCASE SECE SUBUNIT
                     (PROTEIN TRANSPORT PROTEIN SEC61 GAMMA SUBUNIT HOMOLOG)
                     from Sulfolobus acidocaldarius (65 aa), FASTA scores: opt:
                     79, E(): 4.7. (30.3% identity in 66 aa overlap); and
                     hypothetical proteins e.g. Q9HPW4|VNG1446H HYPOTHETICAL
                     PROTEIN from Halobacterium sp. strain NRC-1 (77 aa);
                     Q9I794|PA0038 HYPOTHETICAL PROTEIN from Pseudomonas
                     aeruginosa (71 aa); etc. Also highly similar to
                     U85467|MTU85467_1 hypothetical Mycobacterium tuberculosis
                     protein from a patient isolate (116 aa), FASTA scores:
                     opt: 443, E(): 7.7e-29, (98.6% identity in 71 aa overlap).
                     Note that for Rv0379|MTV036.14, a translation initiation
                     region different to the one in U85467|MTU85467_1 was
                     chosen. COULD BE A PART OF THE PROKARYOTIC PROTEIN
                     TRANSLOCATION APPARATUS WHICH COMPRISE SECA|Rv3240c,
                     SECD|Rv2587c, SECE|Rv0638, SECF|Rv2586c, SECG|Rv1440 AND
                     SECY|Rv0732. Protein product from Mb0386 detected using
                     shotgun mass spectrometry and SWATH mass spectrometry.
                     Mb0386 found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MSVYKVIDII GTSPTSWEQA AAEAVQRARD SVDDIRVARV IEQDMAVDSA GKITYRIKLE
       61 VSFKMRPAQP R
//