LOCUS       CAB5248075.1             344 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            FRUCTOSE-BISPHOSPHATE ALDOLASE FBA protein.
ACCESSION   LT708304-374
PROTEIN_ID  CAB5248075.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="fba"
                     /locus_tag="BQ2027_MB0370C"
                     /standard_name="fda"
                     /note="Mb0370c, fba, len: 344 aa. Equivalent to Rv0363c,
                     len: 344 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 344 aa overlap). Probable fba
                     (alternate gene name: fda), fructose bisphosphate aldolase
                     (EC 4.1.2.13), equivalent to
                     AL023514|MLCB4_18|O69600|ALF_MYCLE FRUCTOSE-BISPHOSPHATE
                     ALDOLASE from Mycobacterium leprae (345 aa), FASTA scores:
                     opt: 1995, E(): 0, (87.7% identity in 342 aa overlap).
                     Also highly similar to others. BELONGS TO CLASS II
                     FRUCTOSE-BISPHOSPHATE ALDOLASE FAMILY. COFACTOR: ZINC.
                     Protein product from Mb0370c detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0370c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing (TPM > 20)."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MPIATPEVYA EMLGQAKQNS YAFPAINCTS SETVNAAIKG FADAGSDGII QFSTGGAEFG
       61 SGLGVKDMVT GAVALAEFTH VIAAKYPVNV ALHTDHCPKD KLDSYVRPLL AISAQRVSKG
      121 GNPLFQSHMW DGSAVPIDEN LAIAQELLKA AAAAKIILEI EIGVVGGEED GVANEINEKL
      181 YTSPEDFEKT IEALGAGEHG KYLLAATFGN VHGVYKPGNV KLRPDILAQG QQVAAAKLGL
      241 PADAKPFDFV FHGGSGSLKS EIEEALRYGV VKMNVDTDTQ YAFTRPIAGH MFTNYDGVLK
      301 VDGEVGVKKV YDPRSYLKKA EASMSQRVVQ ACNDLHCAGK SLTH
//