LOCUS CAB5248075.1 344 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE FRUCTOSE-BISPHOSPHATE ALDOLASE FBA protein. ACCESSION LT708304-374 PROTEIN_ID CAB5248075.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="fba" /locus_tag="BQ2027_MB0370C" /standard_name="fda" /note="Mb0370c, fba, len: 344 aa. Equivalent to Rv0363c, len: 344 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 344 aa overlap). Probable fba (alternate gene name: fda), fructose bisphosphate aldolase (EC 4.1.2.13), equivalent to AL023514|MLCB4_18|O69600|ALF_MYCLE FRUCTOSE-BISPHOSPHATE ALDOLASE from Mycobacterium leprae (345 aa), FASTA scores: opt: 1995, E(): 0, (87.7% identity in 342 aa overlap). Also highly similar to others. BELONGS TO CLASS II FRUCTOSE-BISPHOSPHATE ALDOLASE FAMILY. COFACTOR: ZINC. Protein product from Mb0370c detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0370c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MPIATPEVYA EMLGQAKQNS YAFPAINCTS SETVNAAIKG FADAGSDGII QFSTGGAEFG 61 SGLGVKDMVT GAVALAEFTH VIAAKYPVNV ALHTDHCPKD KLDSYVRPLL AISAQRVSKG 121 GNPLFQSHMW DGSAVPIDEN LAIAQELLKA AAAAKIILEI EIGVVGGEED GVANEINEKL 181 YTSPEDFEKT IEALGAGEHG KYLLAATFGN VHGVYKPGNV KLRPDILAQG QQVAAAKLGL 241 PADAKPFDFV FHGGSGSLKS EIEEALRYGV VKMNVDTDTQ YAFTRPIAGH MFTNYDGVLK 301 VDGEVGVKKV YDPRSYLKKA EASMSQRVVQ ACNDLHCAGK SLTH //