LOCUS       CAB5248064.1             235 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            GRPE PROTEIN (HSP-70 COFACTOR) protein.
ACCESSION   LT708304-363
PROTEIN_ID  CAB5248064.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="grpE"
                     /locus_tag="BQ2027_MB0359"
                     /note="Mb0359, grpE, len: 235 aa. Equivalent to Rv0351,
                     len: 235 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 235 aa overlap). Probable grpE protein
                     (HSP-70 COFACTOR), equivalent to CAC32012.1|AL583925 Hsp70
                     cofactor from Mycobacterium leprae (229 aa). Also highly
                     similar to others eg Q05562|GRPE_STRCO|2127521|PN0643 GRPE
                     PROTEIN from Streptomyces coelicolor (225 aa). Contains
                     grpE protein signature (PS01071). BELONGS TO THE GRPE
                     FAMILY. Protein product from Mb0359 detected using shotgun
                     mass spectrometry and SWATH mass spectrometry. Mb0359
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing (TPM > 20)."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MTDGNQKPDG NSGEQVTVTD KRRIDPETGE VRHVPPGDMP GGTAAADAAH TEDKVAELTA
       61 DLQRVQADFA NYRKRALRDQ QAAADRAKAS VVSQLLGVLD DLERARKHGD LESGPLKSVA
      121 DKLDSALTGL GLVAFGAEGE DFDPVLHEAV QHEGDGGQGS KPVIGTVMRQ GYQLGEQVLR
      181 HALVGVVDTV VVDAAELESV DDGTAVADTA ENDQADQGNS ADTLGEQAES EPSGS
//