LOCUS CAB5248064.1 235 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE GRPE PROTEIN (HSP-70 COFACTOR) protein. ACCESSION LT708304-363 PROTEIN_ID CAB5248064.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="grpE" /locus_tag="BQ2027_MB0359" /note="Mb0359, grpE, len: 235 aa. Equivalent to Rv0351, len: 235 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 235 aa overlap). Probable grpE protein (HSP-70 COFACTOR), equivalent to CAC32012.1|AL583925 Hsp70 cofactor from Mycobacterium leprae (229 aa). Also highly similar to others eg Q05562|GRPE_STRCO|2127521|PN0643 GRPE PROTEIN from Streptomyces coelicolor (225 aa). Contains grpE protein signature (PS01071). BELONGS TO THE GRPE FAMILY. Protein product from Mb0359 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0359 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing (TPM > 20)." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTDGNQKPDG NSGEQVTVTD KRRIDPETGE VRHVPPGDMP GGTAAADAAH TEDKVAELTA 61 DLQRVQADFA NYRKRALRDQ QAAADRAKAS VVSQLLGVLD DLERARKHGD LESGPLKSVA 121 DKLDSALTGL GLVAFGAEGE DFDPVLHEAV QHEGDGGQGS KPVIGTVMRQ GYQLGEQVLR 181 HALVGVVDTV VVDAAELESV DDGTAVADTA ENDQADQGNS ADTLGEQAES EPSGS //