LOCUS       CAB5248038.1             226 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY)
            protein.
ACCESSION   LT708304-337
PROTEIN_ID  CAB5248038.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0332"
                     /note="Mb0332, -, len: 226 aa. Equivalent to Rv0324, len:
                     226 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.6% identity in 226 aa overlap). Possible
                     transcriptional regulator, arsR family, with its
                     N-terminus similar to the N-terminus of other DNA-binding
                     proteins e.g. P30346|MERR_STRLI probable mercury
                     resistance operon from Streptomyces lividans (125 aa),
                     FASTA scores: opt: 154, E(): 0.002, (32.2% identity in 90
                     aa overlap)), and its C-terminal part similar to
                     hypothetical bacterial proteins e.g. P54510|YQHL_BACSU
                     hypothetical 14.6 kd protein from Bacillus subtilis (126
                     aa), FASTA scores: opt: 159, E(): 0.00097, (35.5% identity
                     in 76 aa overlap)). Most similar to AJ005575|SPE005575_2
                     ORF1 required for antibiotic production from Streptomyces
                     peucetius (226 aa), FASTA scores: opt: 816, E(): 0, (60.7%
                     identity in 211 aa overlap). Also similar in C-terminus to
                     MTCY164.26 molybdopterin biosynthesis moeb protein from
                     Mycobacterium tuberculosis FASTA score: (36.8% identity in
                     114 aa overlap). Protein product from Mb0332 detected
                     using SWATH mass spectrometry."
BEGIN
        1 MAGQSDRKAA LLDQVARVGK ALANGRRLQI LDLLAQGERA VEAIATATGM NLTTASANLQ
       61 ALKSGGLVEA RREGTRQYYR IAGEDVARLF ALVQVVADEH LADVAVAAAD VLGSPEDAIT
      121 RAELLRRREA GEVTLVDVRP HEEYQAGHIP GAINIPIAEL ADRLAELAGD RDIVAYCRGA
      181 YCVMAPDAVR IARDAGREVK RLDDGMLEWR LAGLPVDEGA PVGHGD
//