LOCUS CAB5248035.1 190 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE) protein. ACCESSION LT708304-334 PROTEIN_ID CAB5248035.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="dcd" /locus_tag="BQ2027_MB0329" /note="Mb0329, dcd, len: 190 aa. Equivalent to Rv0321, len: 190 aa, from Mycobacterium tuberculosis strain H37Rv, (99.5% identity in 190 aa overlap). Probable dcd (alterrnate gene names: dus or paxA), deoxycytidine triphosphate deaminase (EC 3.5.4.13), equivalent to CAC32024.1|AL583925 probable deoxycytidine triphosphate deaminase from Mycobacterium leprae (190 aa). Also highly similar to others e.g. Q9X8W0|DCD_STRCO|7480599|T36613|SCH35.46 DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE from Streptomyces coelicolor (191 aa); DCD_ECOLI|P28248|DUS|PAXA|B2065 DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE from Escherichia coli strain K12 (193 aa), FASTA scores: opt: 408, E(): 2.7e-21, (43.1% identity in 188 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE DCTP DEAMINASE FAMILY. Protein product from Mb0329 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0329 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MLLSDRDLRA EISSGRLGID PFDDTLVQPS SIDVRLDCLF RVFNNTRYTH IDPAKQQDEL 61 TSLVQPVDGE PFVLHPGEFV LGSTLELFTL PDNLAGRLEG KSSLGRLGLL THSTAGFIDP 121 GFSGHITLEL SNVANLPITL WPGMKIGQLC MLRLTSPSEH PYGSSRAGSK YQGQRGPTPS 181 RSCQNFIRST //