LOCUS       CAB5248033.1             222 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            PYRROLIDONE-CARBOXYLATE PEPTIDASE PCP (5-OXOPROLYL-PEPTIDASE)
            (PYROGLUTAMYL-PEPTIDASE I) (PGP-I) (PYRASE) protein.
ACCESSION   LT708304-332
PROTEIN_ID  CAB5248033.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="pcp"
                     /locus_tag="BQ2027_MB0327"
                     /note="Mb0327, pcp, len: 222 aa. Equivalent to Rv0319,
                     len: 222 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 222 aa overlap). Probable pcp,
                     pyrrolidone-carboxylate peptidase (EC 3.4.19.3), highly
                     similar to others e.g. PCP_PSEFL|P42673
                     pyrrolidone-carboxylate peptidase from Pseudomonas
                     fluorescens (213 aa), FASTA scores: opt: 478, E():
                     7.5e-25, (40.2% identity in 219 aa overlap). BELONGS TO
                     PEPTIDASE FAMILY C15 (THIOL PROTEASE). Protein product
                     from Mb0327 detected using SWATH mass spectrometry. Mb0327
                     found to be expressed during exponential growth in
                     Sauton's minimal media by RNA-sequencing."
BEGIN
        1 MSKVLVTGFG PYGVTPVNPA QLTAEELDGR TIAGATVISR IVPNTFFESI AAAQQAIAEI
       61 EPALVIMLGE YPGRSMITVE RLAQNVNDCG RYGLADCAGR VLVGEPTDPA GPVAYHATVP
      121 VRAMVLAMRK AGVPADVSDA AGTFVCNHLM YGVLHHLAQK GLPVRAGWIH LPCLPSVAAL
      181 DHNLGVPSMS VQTAVAGVTA GIEAAIRQSA DIREPIPSRL QI
//