LOCUS       CAB5248030.1             204 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            MUCONOLACTONE ISOMERASE protein.
ACCESSION   LT708304-329
PROTEIN_ID  CAB5248030.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0324"
                     /note="Mb0324, -, len: 204 aa. Equivalent to Rv0316, len:
                     204 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 204 aa overlap). Possible
                     muconolactone isomerase (EC 5.3.3.-), showing weak
                     similarity with some muconolactone isomerases e.g.
                     O33947|CTC1_ACILW MUCONOLACTONE DELTA-ISOMERASE 1 (MIASE
                     1)(96 aa), FASTA scores: opt: 179, E(): 3.9e-05, (32.6%
                     identity in 92 aa overlap). Protein product from Mb0324
                     detected using SWATH mass spectrometry. Mb0324 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MEFLVTMTTR VPDSMPADAV ERVRAREAAR SRELAAQGKL LRLWRPPLRP GEWRTLGLFA
       61 ADDNGELEQL LASMPPRSWR TDDVTPLGAH PNDPVGQGIT IAPGKGPEFL IATTIMVPPG
      121 TPAQVVDDTV AREARRAPEL AGRGHLVRLW ALPDGPDGQR TLGLWRARDP GELMAILESL
      181 PLAGWMTIET TPLSPHPDDP IRMP
//