LOCUS       CAB5248029.1             294 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            BETA-1,3-GLUCANASE PRECURSOR protein.
ACCESSION   LT708304-328
PROTEIN_ID  CAB5248029.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0323"
                     /note="Mb0323, -, len: 294 aa. Equivalent to Rv0315, len:
                     294 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 294 aa overlap). Possible
                     beta-1,3-glucanase precursor (EC 3.2.1.-) (has hydrophobic
                     stretch in its N-terminal part), similar to others e.g.
                     Q51333|AAC44371.1 BETA-1,3-GLUCANASE II A from Oerskovia
                     xanthineolytica (306 aa), FASTA scores: opt: 76, E():
                     3e-14, (34.1% identity in 302 aa overlap); and
                     AAC38290.1|AF052745 beta-1,3-glucanase II from Oerskovia
                     xanthineolytica (435 aa). Contains glycosyl hydrolases
                     family 16 active site signature (PS01034). Protein product
                     from Mb0323 detected using shotgun mass spectrometry and
                     SWATH mass spectrometry. Mb0323 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MLMPEMDRRR MMMMAGFGAL AAALPAPTAW ADPSRPAAPA GPTPAPAAPA AATGGLLFHD
       61 EFDGPAGSVP DPSKWQVSNH RTPIKNPVGF DRPQFFGQYR DSRQNVFLDG NSNLVLRATR
      121 EGNRYFGGLV HGLWRGGIGT TWEARIKFNC LAPGMWPAWW LSNDDPGRSG EIDLIEWYGN
      181 GTWPSGTTVH ANPDGTAFET CPIGVDGGWH NWRVTWNPSG MYFWLDYADG IEPYFSVPAT
      241 GIEDLNEPIR EWPFNDPGYT VFPVLNLAVG GSGGGDPATG SYPQEMLVDW VRVF
//