LOCUS       CAB5248024.1             163 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Bile
            acid 7-alpha dehydratase BaiE (EC protein.
ACCESSION   LT708304-323
PROTEIN_ID  CAB5248024.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0318C"
                     /EC_number="4.2.1.106"
                     /note="Mb0318c, -, len: 163 aa. Equivalent to Rv0310c,
                     len: 163 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 163 aa overlap). Conserved
                     hypothetical protein, similar to some bile acid
                     dehydratases e.g. P19412|BAIE_EUBSP|98749|D37844|1381566|A
                     AC45413.1|U57489 BILE ACID-INDUCIBLE OPERON PROTEIN E from
                     Eubacterium sp (166 aa), FASTA scores: opt: 302, E():
                     1e-11, (38.8% identity in 134 aa overlap);
                     AAF22847.1|AF210152_4 bile acid 7a-dehydratase from
                     Clostridium sp. (168 aa). Protein product from Mb0318c
                     detected using shotgun mass spectrometry. Mb0318c found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MCCNGVVTPG DPADIAAIKQ LKYRYLRALD TKHWDDFTDT LAEDVTGDYG SSVGTELHFT
       61 NRADLVDYLR QALGPGVITE HRVTHPEITV TGDTATGIWY LQDRVIVAEF NFMLIGAAFY
      121 HDQYRRTTDG WRISATGYDR TYEATMSLAG LNFNIRPGRA LAD
//