LOCUS CAB5248024.1 163 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 Bile acid 7-alpha dehydratase BaiE (EC protein. ACCESSION LT708304-323 PROTEIN_ID CAB5248024.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0318C" /EC_number="4.2.1.106" /note="Mb0318c, -, len: 163 aa. Equivalent to Rv0310c, len: 163 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 163 aa overlap). Conserved hypothetical protein, similar to some bile acid dehydratases e.g. P19412|BAIE_EUBSP|98749|D37844|1381566|A AC45413.1|U57489 BILE ACID-INDUCIBLE OPERON PROTEIN E from Eubacterium sp (166 aa), FASTA scores: opt: 302, E(): 1e-11, (38.8% identity in 134 aa overlap); AAF22847.1|AF210152_4 bile acid 7a-dehydratase from Clostridium sp. (168 aa). Protein product from Mb0318c detected using shotgun mass spectrometry. Mb0318c found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MCCNGVVTPG DPADIAAIKQ LKYRYLRALD TKHWDDFTDT LAEDVTGDYG SSVGTELHFT 61 NRADLVDYLR QALGPGVITE HRVTHPEITV TGDTATGIWY LQDRVIVAEF NFMLIGAAFY 121 HDQYRRTTDG WRISATGYDR TYEATMSLAG LNFNIRPGRA LAD //