LOCUS       CAB5248022.1             238 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED INTEGRAL MEMBRANE PROTEIN protein.
ACCESSION   LT708304-321
PROTEIN_ID  CAB5248022.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0316"
                     /note="Mb0316, -, len: 238 aa. Equivalent to Rv0308, len:
                     238 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 238 aa overlap). Probable conserved
                     integral membrane protein, with C-terminus highly similar
                     to C-terminus of other integral membrane proteins or
                     phosphatases e.g. AAK25788.1|AF336822_1|13430250|AAK25789.
                     1|AF336823_1 putative phosphatase from Streptococcus
                     pyogenes (201 aa); Q06074 HYPOTHETICAL 24.9 KD PROTEIN
                     (216 aa), FASTA scores: opt: 209, E(): 2e-07, (27.9%
                     identity in 140 aa overlap). Could be a phosphatase.
                     Protein product from Mb0316 detected using shotgun mass
                     spectrometry and SWATH mass spectrometry. Mb0316 found to
                     be expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MTRPQALLAV SLAFVATAVY AVMWVGHSQD WGWLHSFDWS LLNAAHDIGI KNPAWVRFWD
       61 GVSLILGPVV LRPLGLLAAM VALAKRKIRI ALLLLACLPL NAIMTIAAKS VAHRPRPATA
      121 LVSAHSTSFP SGHALEATAS VLALLTVLLP MLHSRFTRHI AITVGALCVL TVGVARVALN
      181 VHHPTDVVAG WALGYLYFLV CLCVFRPPSI FGAQRASHAL SPPVEVSRQP EPEVDTAR
//