LOCUS       CAB5248018.1            1147 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe5 protein.
ACCESSION   LT708304-317
PROTEIN_ID  CAB5248018.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE5"
                     /locus_tag="BQ2027_MB0312C"
                     /note="Mb0312c, PPE5, len: 1147 aa. Equivalent to 3' end
                     of Rv0304c, len: 2204 aa, from Mycobacterium tuberculosis
                     strain H37Rv, (99.9% identity in 1147 aa overlap). Member
                     of the Mycobacterium tuberculosis PE family (PPE, MPTR),
                     similar to others e.g. Z95324|MTY13E10_16 from M.
                     tuberculosis (1443 aa), FASTA scores: E(): 0, (50.6%
                     identity in 1403 aa overlap); Y04H_MYCTU|Q10778 from M.
                     tuberculosis (734 aa), FASTA scores: opt: 989, E(): 0,
                     (42.3% identity in 522 aa overlap).
                     REMARK-M.bovis-M.tuberculosis: In Mycobacterium
                     tuberculosis strain H37Rv, PPE5 and PPE6 exist as separate
                     genes. In Mycobacterium bovis, a frameshift due to a
                     single base deletion (g-*) leads to a shorter CDS
                     (Mb0312c) equivalent to the 3' end of Rv0304c/PPE5."
BEGIN
        1 MFNSGDGNIG FFNSGTGNFG IGNTGTGNFG IGNSGSTSTG LFNSGDGNTG GFNPGNFNTG
       61 NFNTGSFNTG GFNAGNTNTG HFNTGNYNTG IANTGDVSTG AFISGNYSNG ILWRGDYQGL
      121 IGYSYALTIP EIPAHLDVNI PIDIPITGSF TDLVVDNFTI PIIGFESFAF SFHIHTEPDI
      181 GPIIVPSFVL SVPTFAIAVG GPTTAINISA TAGLGPITIP IIDIPAAPGI GNSTTSPSSG
      241 FFNTGAGTAS GFGNVGGNTS GLWNLASAAS GVSGLLNVGA LGSGVANVGN TISGIYNTSP
      301 LDLGTPAFGS GLANIAGLLQ GGAGTTILDL AGLGNLNVGL ANLGGSNFGI GNTGIFNVGF
      361 ANVGNHNIGL ANLGNYSVGF ANSGNYHIGI ANTGSANIGF ANTGSGNIGI GLTGTGQIGF
      421 GSFNSGSHNI GLFNSGDGNV GFFNSGTGNV GIGNTGTANF GIANSGSFNT GLGNTGSTNT
      481 SLFNPGNVNT GVGNTGSINT GSFNTGSTNT GSFNLGDHNT GSFNSGDYNT GYFNAGDYNT
      541 GVANTGNVNT GAFISGNYSN GFFWRGDYQG LIGLSTTITI PEIPYRYDLS VPIDIPITGT
      601 VVATTPNSFT IPGFQIRVLL GPAAVLVNEM IGPITIDVNQ VIAIDSPIQQ TISMVGTGGF
      661 GPIPIGISIG GTPGFGNSTT GPSSGFFHTG AGHVSGFGNF GAGNMSGFGN FGAGNSGFFN
      721 AGGLGNSGLL NFGALQSGLA NLGNTISGVY NTSTLDLATP AFGSGIANIG ANLAGLFLDN
      781 TGNLTLNFGV ANQGGLNAGI GNLGSVNIGF VNTGDSNLGI GNLGDLNFGG VNIGGNNIGI
      841 ANTGIFDIGL ANLGSYNIGL ANLGDDNLGF GNAGSYNIGF ANFGSDNLGF ANTGSYNIGF
      901 ANTGNNNIGV GLTGNGQIGI GSLNSGSNNI GLFNSGSGNI GFFNSGTGNV GIFNAGTGNF
      961 GLANSGGFNT GIGNAGSTNT GVFNPGDLNT GSFNPGSFNT GGFNPGSGNT GYLNTGDYNT
     1021 GVANTGDVDT GAFITGSYSN GFLVSGDYQG LIGLPLLGIP VTPGYFNLTG GPSSGFFNSG
     1081 AGSVSGFVNS GAGLSGYLNT GALGSGVANV GNTISGWLNA SALDLATPGF LSGIGNFGTN
     1141 LAGFFRG
//