LOCUS CAB5248018.1 1147 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe5 protein. ACCESSION LT708304-317 PROTEIN_ID CAB5248018.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE5" /locus_tag="BQ2027_MB0312C" /note="Mb0312c, PPE5, len: 1147 aa. Equivalent to 3' end of Rv0304c, len: 2204 aa, from Mycobacterium tuberculosis strain H37Rv, (99.9% identity in 1147 aa overlap). Member of the Mycobacterium tuberculosis PE family (PPE, MPTR), similar to others e.g. Z95324|MTY13E10_16 from M. tuberculosis (1443 aa), FASTA scores: E(): 0, (50.6% identity in 1403 aa overlap); Y04H_MYCTU|Q10778 from M. tuberculosis (734 aa), FASTA scores: opt: 989, E(): 0, (42.3% identity in 522 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PPE5 and PPE6 exist as separate genes. In Mycobacterium bovis, a frameshift due to a single base deletion (g-*) leads to a shorter CDS (Mb0312c) equivalent to the 3' end of Rv0304c/PPE5." BEGIN 1 MFNSGDGNIG FFNSGTGNFG IGNTGTGNFG IGNSGSTSTG LFNSGDGNTG GFNPGNFNTG 61 NFNTGSFNTG GFNAGNTNTG HFNTGNYNTG IANTGDVSTG AFISGNYSNG ILWRGDYQGL 121 IGYSYALTIP EIPAHLDVNI PIDIPITGSF TDLVVDNFTI PIIGFESFAF SFHIHTEPDI 181 GPIIVPSFVL SVPTFAIAVG GPTTAINISA TAGLGPITIP IIDIPAAPGI GNSTTSPSSG 241 FFNTGAGTAS GFGNVGGNTS GLWNLASAAS GVSGLLNVGA LGSGVANVGN TISGIYNTSP 301 LDLGTPAFGS GLANIAGLLQ GGAGTTILDL AGLGNLNVGL ANLGGSNFGI GNTGIFNVGF 361 ANVGNHNIGL ANLGNYSVGF ANSGNYHIGI ANTGSANIGF ANTGSGNIGI GLTGTGQIGF 421 GSFNSGSHNI GLFNSGDGNV GFFNSGTGNV GIGNTGTANF GIANSGSFNT GLGNTGSTNT 481 SLFNPGNVNT GVGNTGSINT GSFNTGSTNT GSFNLGDHNT GSFNSGDYNT GYFNAGDYNT 541 GVANTGNVNT GAFISGNYSN GFFWRGDYQG LIGLSTTITI PEIPYRYDLS VPIDIPITGT 601 VVATTPNSFT IPGFQIRVLL GPAAVLVNEM IGPITIDVNQ VIAIDSPIQQ TISMVGTGGF 661 GPIPIGISIG GTPGFGNSTT GPSSGFFHTG AGHVSGFGNF GAGNMSGFGN FGAGNSGFFN 721 AGGLGNSGLL NFGALQSGLA NLGNTISGVY NTSTLDLATP AFGSGIANIG ANLAGLFLDN 781 TGNLTLNFGV ANQGGLNAGI GNLGSVNIGF VNTGDSNLGI GNLGDLNFGG VNIGGNNIGI 841 ANTGIFDIGL ANLGSYNIGL ANLGDDNLGF GNAGSYNIGF ANFGSDNLGF ANTGSYNIGF 901 ANTGNNNIGV GLTGNGQIGI GSLNSGSNNI GLFNSGSGNI GFFNSGTGNV GIFNAGTGNF 961 GLANSGGFNT GIGNAGSTNT GVFNPGDLNT GSFNPGSFNT GGFNPGSGNT GYLNTGDYNT 1021 GVANTGDVDT GAFITGSYSN GFLVSGDYQG LIGLPLLGIP VTPGYFNLTG GPSSGFFNSG 1081 AGSVSGFVNS GAGLSGYLNT GALGSGVANV GNTISGWLNA SALDLATPGF LSGIGNFGTN 1141 LAGFFRG //