LOCUS       CAB5248008.1             261 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANS-ACONITATE METHYLTRANSFERASE TAM protein.
ACCESSION   LT708304-307
PROTEIN_ID  CAB5248008.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="tam"
                     /locus_tag="BQ2027_MB0302"
                     /note="Mb0302, tam, len: 261 aa. Equivalent to Rv0294,
                     len: 261 aa, from Mycobacterium tuberculosis strain H37Rv
                     (100.0% identity in 261 aa overlap). Probable tam,
                     trans-aconitate methyltransferase (EC 2.1.1.-), similar to
                     others e.g. P76145|TAM_ECOLI|7465793|B64906|B1519
                     TRANS-ACONITATE METHYLTRANSFERASE from Escherichia coli
                     strain K12 (252 aa), FASTA scores: opt: 649, E(): 0, (39.3
                     identity in 252 aa overlap). BELONGS TO THE
                     METHYLTRANSFERASE SUPERFAMILY. Protein product from Mb0302
                     detected using SWATH mass spectrometry. Mb0302 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MWDPDVYLAF SGHRNRPFYE LVSRVGLERA RRVVDLGCGP GHLTRYLARR WPGAVIEALD
       61 SSPEMVAAAA ERGIDATTGD LRDWKPKPDT DVVVSNAALH WVPEHSDLLV RWVDELAPGS
      121 WIAVQIPGNF ETPSHAAVRA LARREPYAKL MRDIPFRVGA VVQSPAYYAE LLMDTGCKVD
      181 VWETTYLHQL TGEHPVLDWI TGSALVPVRE RLSDESWQQF RQELIPLLND AYPPRADGST
      241 IFPFRRLFMV AEVGGARRSG G
//