LOCUS       CAB5248004.1             472 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 esx
            conserved component eccd3. esx-3 type vii secretion system
            protein. probable transmembrane protein. protein.
ACCESSION   LT708304-303
PROTEIN_ID  CAB5248004.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="eccd3"
                     /locus_tag="BQ2027_MB0298"
                     /note="Mb0298, -, len: 472 aa. Equivalent to Rv0290, len:
                     472 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 472 aa overlap). Probable conserved
                     transmembrane protein, similar to several others in
                     mycobacteria e.g. Z95389|MTCY77_20|Rv3887c from
                     Mycobacterium tuberculosis (467 aa), FASTA scores: opt:
                     429, E(): 5.1e-19, (28. 6% identity in 479 aa overlap);
                     Rv3877; Rv1795; Rv3448; and Y14967|MLCB628_9|MLCB628.10c
                     from Mycobacterium leprae (480 aa), FASTA scores: opt:
                     269, E(): 3.1e-09, (26.0% identity in 503 aa overlap).
                     TBparse score is 0.892. Protein product from Mb0298
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0298 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSGTVMQIVR VAILADSRLT EMALPAELPL REILPAVQRL VVPSAQNGDG GQADSGAAVQ
       61 LSLAPVGGQP FSLDASLDTV GVVDGDLLVL QPVPAGPAAP GIVEDIADAA MIFSTSRLKP
      121 WGIAHIQRGA LAAVIAVALL ATGLTVTYRV ATGVLAGLLA VAGIAVASAL AGLLITIRSP
      181 RSGIALSIAA LVPIGAALAL AVPGKFGPAQ VLLGAAGVAA WSLIALMIPS AERERVVAFF
      241 TAAAVVGASV ALAAGAQLLW QLPLLSIGCG LIVAALLVTI QAAQLSALWA RFPLPVIPAP
      301 GDPTPSAPPL RLLEDLPRRV RVSDAHQSGF IAAAVLLSVL GSVAIAVRPE ALSVVGWYLV
      361 AATAAAATLR ARVWDSAACK AWLLAQPYLV AGVLLVFYTT TGRYVAAFGA VLVLAVLMLA
      421 WVVVALNPGI ASPESYSLPL RRLLGLVAAG LDVSLIPVMA YLVGLFAWVL NR
//