LOCUS CAB5248004.1 472 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 esx conserved component eccd3. esx-3 type vii secretion system protein. probable transmembrane protein. protein. ACCESSION LT708304-303 PROTEIN_ID CAB5248004.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="eccd3" /locus_tag="BQ2027_MB0298" /note="Mb0298, -, len: 472 aa. Equivalent to Rv0290, len: 472 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 472 aa overlap). Probable conserved transmembrane protein, similar to several others in mycobacteria e.g. Z95389|MTCY77_20|Rv3887c from Mycobacterium tuberculosis (467 aa), FASTA scores: opt: 429, E(): 5.1e-19, (28. 6% identity in 479 aa overlap); Rv3877; Rv1795; Rv3448; and Y14967|MLCB628_9|MLCB628.10c from Mycobacterium leprae (480 aa), FASTA scores: opt: 269, E(): 3.1e-09, (26.0% identity in 503 aa overlap). TBparse score is 0.892. Protein product from Mb0298 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0298 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MSGTVMQIVR VAILADSRLT EMALPAELPL REILPAVQRL VVPSAQNGDG GQADSGAAVQ 61 LSLAPVGGQP FSLDASLDTV GVVDGDLLVL QPVPAGPAAP GIVEDIADAA MIFSTSRLKP 121 WGIAHIQRGA LAAVIAVALL ATGLTVTYRV ATGVLAGLLA VAGIAVASAL AGLLITIRSP 181 RSGIALSIAA LVPIGAALAL AVPGKFGPAQ VLLGAAGVAA WSLIALMIPS AERERVVAFF 241 TAAAVVGASV ALAAGAQLLW QLPLLSIGCG LIVAALLVTI QAAQLSALWA RFPLPVIPAP 301 GDPTPSAPPL RLLEDLPRRV RVSDAHQSGF IAAAVLLSVL GSVAIAVRPE ALSVVGWYLV 361 AATAAAATLR ARVWDSAACK AWLLAQPYLV AGVLLVFYTT TGRYVAAFGA VLVLAVLMLA 421 WVVVALNPGI ASPESYSLPL RRLLGLVAAG LDVSLIPVMA YLVGLFAWVL NR //