LOCUS CAB5248003.1 295 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 esx- 3 secretion-associated protein espg3 protein. ACCESSION LT708304-302 PROTEIN_ID CAB5248003.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="espg3" /locus_tag="BQ2027_MB0297" /note="Mb0297, -, len: 295 aa. Equivalent to Rv0289, len: 295 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 295 aa overlap). Conserved hypothetical protein, equivalent to CAC32061.1|AL583926 possible DNA-binding protein from Mycobacterium leprae (289 aa); and showing some similarity to Rv3866|G70656|CAB06238.1|Z94121|MTCY15F10.23 from Mycobacterium tuberculosis (276 aa), FASTA scores: opt: 149, E(): 0.0035, (27.7% identity in 289 aa overlap). Protein product from Mb0297 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0297 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MDATPNAVEL TVDNAWFIAE TIGAGTFPWV LAITMPYSDA AQRGAFVDRQ RDELTRMGLL 61 SPQGVINPAV ADWIKVVCFP DRWLDLRYVG PASADGACEL LRGIVALRTG TGKTSNKTGN 121 GVVALRNAQL VTFTAMDIDD PRALVPILGV GLAHRPPARF DEFSLPTRVG ARADERLRSG 181 VPLGEVVDYL GIPASARPVV ESVFSGPRSY VEIVAGCNRD GRHTTTEVGL SIVDTSAGRV 241 LVSPSRAFDG EWVSTFSPGT PFAIAVAIQT LTACLPDGQW FPGQRVSRDF STQSS //