LOCUS       CAB5248002.1              96 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 low
            molecular weight protein antigen 7 esxh (10 kda antigen)
            (cfp-7) (protein tb10.4) protein.
ACCESSION   LT708304-301
PROTEIN_ID  CAB5248002.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="esxH"
                     /locus_tag="BQ2027_MB0296"
                     /standard_name="cfp7; TB10.4"
                     /note="Mb0296, esxH, len: 96 aa. Equivalent to Rv0288,
                     len: 96 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 96 aa overlap). esxH (alternate gene
                     name: TB10.4), low molecular weight protein antigen 7 (10
                     kDa antigen) (CFP-7) (Protein TB10.4) (see citations
                     below), ala-rich protein; member of mycobacterial protein
                     family containing ESAT-6, very similar to MTV012_33 from
                     Mycobacterium tuberculosis (96 aa), FASTA scores: opt:
                     566, E(): 0, (84.4% identity in 96 aa overlap).
                     Alternative start codon possible position 351878 (see
                     second citation). BELONG TO THE ESAT6 FAMILY (see first,
                     sixth and seventh citations below). Protein product from
                     Mb0296 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0296 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MSQIMYNYPA MLGHAGDMAG YAGTLQSLGA EIAVEQAALQ SAWQGDTGIT YQAWQAQWNQ
       61 AMEDLVRAYH AMSSTHEANT MAMMARDTAE AAKWGG
//