LOCUS CAB5247997.1 538 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 esx conserved component eccb3. esx-3 type vii secretion system protein. possible membrane protein. protein. ACCESSION LT708304-296 PROTEIN_ID CAB5247997.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="eccb3" /locus_tag="BQ2027_MB0291" /note="Mb0291, -, len: 538 aa. Equivalent to Rv0283, len: 538 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 538 aa overlap). Possible conserved membrane protein, similar to several hypothetical mycobacterial proteins e.g. Z94121|MTY15F10_16|Rv3895c from Mycobacterium tuberculosis (495 aa), FASTA scores: opt: 698, E(): 0, (37.6% identity in 492 aa overlap); Rv1782; Rv3450c; Rv3869; and Y14967|MLCB628_16|MLCB628.17c from Mycobacterium leprae (481 aa), FASTA scores: opt: 672, E(): 1.5e-31, (37.2% identity in 506 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop). Protein product from Mb0291 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0291 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." /experiment="experimental evidence, no additional details recorded" BEGIN 1 MTNQQHDHDF DHDRRSFASR TPVNNNPDKV VYRRGFVTRH QVTGWRFVMR RIAAGIALHD 61 TRMLVDPLRT QSRAVLMGVL IVITGLIGSF VFSLIRPNGQ AGSNAVLADR STAALYVRVG 121 EQLHPVLNLT SARLIVGRPV SPTTVKSTEL DQFPRGNLIG IPGAPERMVQ NTSTDANWTV 181 CDGLNAPSRG GADGVGVTVI AGPLEDTGAR AAALGPGQAV LVDSGAGTWL LWDGKRSPID 241 LADHAVTSGL GLGADVPAPR IIASGLFNAI PEAPPLTAPI IPDAGNPASF GVPAPIGAVV 301 SSYALKDSGK TISDTVQYYA VLPDGLQQIS PVLAAILRNN NSYGLQQPPR LGADEVAKLP 361 VSRVLDTRRY PSEPVSLVDV TRDPVTCAYW SKPVGAATSS LTLLAGSALP VPDAVHTVEL 421 VGAGNGGVAT RVALAAGTGY FTQTVGGGPD APGAGSLFWV SDTGVRYGID NEPQGVAGGG 481 KAVEALGLNP PPVPIPWSVL SLFVPGPTLS RADALLAHDT LVPDSRPARP VSAEGGYR //