LOCUS       CAB5247994.1             536 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 ppe
            family protein ppe3 protein.
ACCESSION   LT708304-293
PROTEIN_ID  CAB5247994.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="PPE3"
                     /locus_tag="BQ2027_MB0288"
                     /note="Mb0288, PPE3, len: 536 aa. Equivalent to Rv0280,
                     len: 536 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.8% identity in 536 aa overlap). Member of the
                     Mycobacterium tuberculosis PPE family, similar to others
                     e.g. Z80108|MTCY21B4_4|Rv0453 from Mycobacterium
                     tuberculosis (539 aa), FASTA scores: opt: 1131, E(): 0,
                     (51.7% identity in 540 aa overlap). Protein product from
                     Mb0288 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0288 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MTLWMASPPE VHSALLSSGP GPGSVLSAAG VWSSLSAEYA AVADELIGLL GAVQTGAWQG
       61 PSAAAYVAAH APYLAWLMRA SETSAEAAAR HETVAAAYTT AVAAMPTLVE LAANHTLHGV
      121 LVATNFFGIN TIPIALNEAD YARMWTQAAS TMATYQAVAE AAVASAPQTT PAPPILAAEA
      181 ADDDHDHDHD HGGEPTPLDY LVAEILRIIS GGRLIWDPAE GTMNGIPFED YTDAAQPIWW
      241 VVRAIEFSKD FETFVQELFV NPVEAFQFYF ELLLFDYPTH IVQIVEALSQ SPQLLAVALG
      301 SVISNLGAVT GFAGLSGLAG MQPAAIPALA PVAAAPPTLP AVAMAPTMAA PGAAVASAAA
      361 PASAPAASTV ASATPAPPPA PGAAGFGYPY AIAPPGIGFG SGMSASASAQ RKAPQPDSAA
      421 AAAAAAAVRD QARARRRRRV TRRGYGDEFM DMNIDVDPDW GPPPGEDPVT STVASDRGAG
      481 HLGFAGTARR EAVADAAGMT TLAGDDFGDG PTTPMVPGSW DPDRDAPGSA EPGDRG
//