LOCUS CAB5247994.1 536 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 ppe family protein ppe3 protein. ACCESSION LT708304-293 PROTEIN_ID CAB5247994.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="PPE3" /locus_tag="BQ2027_MB0288" /note="Mb0288, PPE3, len: 536 aa. Equivalent to Rv0280, len: 536 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 536 aa overlap). Member of the Mycobacterium tuberculosis PPE family, similar to others e.g. Z80108|MTCY21B4_4|Rv0453 from Mycobacterium tuberculosis (539 aa), FASTA scores: opt: 1131, E(): 0, (51.7% identity in 540 aa overlap). Protein product from Mb0288 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0288 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MTLWMASPPE VHSALLSSGP GPGSVLSAAG VWSSLSAEYA AVADELIGLL GAVQTGAWQG 61 PSAAAYVAAH APYLAWLMRA SETSAEAAAR HETVAAAYTT AVAAMPTLVE LAANHTLHGV 121 LVATNFFGIN TIPIALNEAD YARMWTQAAS TMATYQAVAE AAVASAPQTT PAPPILAAEA 181 ADDDHDHDHD HGGEPTPLDY LVAEILRIIS GGRLIWDPAE GTMNGIPFED YTDAAQPIWW 241 VVRAIEFSKD FETFVQELFV NPVEAFQFYF ELLLFDYPTH IVQIVEALSQ SPQLLAVALG 301 SVISNLGAVT GFAGLSGLAG MQPAAIPALA PVAAAPPTLP AVAMAPTMAA PGAAVASAAA 361 PASAPAASTV ASATPAPPPA PGAAGFGYPY AIAPPGIGFG SGMSASASAQ RKAPQPDSAA 421 AAAAAAAVRD QARARRRRRV TRRGYGDEFM DMNIDVDPDW GPPPGEDPVT STVASDRGAG 481 HLGFAGTARR EAVADAAGMT TLAGDDFGDG PTTPMVPGSW DPDRDAPGSA EPGDRG //