LOCUS CAB5247979.1 463 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 probable integral membrane nitrite extrusion protein naru (nitrite facilitator) protein. ACCESSION LT708304-278 PROTEIN_ID CAB5247979.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="narU" /locus_tag="BQ2027_MB0273" /note="Mb0273, narU, len: 463 aa. Equivalent to Rv0267, len: 463 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 463 aa overlap). Probable narU, nitrite extrusion protein, integral membrane protein possibly member of major facilitator superfamily (MFS), similar to other nitrite extrusion proteins e.g. NARU_ECOLI|P37758 nitrite extrusion protein 2 from Escherichia coli (462 aa), FASTA scores: opt: 630, E(): 4.4e-33, (38.9% identity in 463 aa overlap); and NARK_ECOLI|P10903|B1223 nitrite extrusion protein 1 from Escherichia coli strain K12 (463 aa), FASTA scores: opt: 607, E(): 1.3e-31, (42.0% identity in 457 aa overlap). Also similar to Rv0261c, Rv2329c, Rv1737c, and to MLCB22_25 from Mycobacterium leprae (517 aa), FASTA score: (35.1 identity in 459 aa overlap). BELONGS TO THE NARK/NASA FAMILY OF TRANSPORTERS. Protein product from Mb0273 detected using SWATH mass spectrometry." BEGIN 1 MALTTAPAID YALPRQQDEG DHWIDDWRPE DPVFWETIGR PIARRNLIFS IFAEHVGFSV 61 WMLWSIVVVQ MTAAAPGHPA ASGWALSASQ ALCLVAVPSG VGAFLRLPYT FAIPIFGGRN 121 WTTVSAALLV IPCLLLAWAV SHPSLPFAVL VVIAATAGFG GGNFASSMAN ISFFYPEKDK 181 GWALGLNAAG GNIGVAVVQK IIPPIVVAGS GVALSRAGLF FVPLAVAAAV CAFLFMNNLT 241 EAKADVKPVW QSLRHADTWI MSLLYIGTFG SFIGYSAAFP TLLKTVFGRG DIALGWAFLG 301 AGIGSLVRPL GGKLADRIGG ARITAASFVM LAAGAAAALW SVQSVNLPVF FVSFMFLFVA 361 TGIGNGSSYR MISRIFQVKG EVAGGDPETM VNMRRQAAGA LGIISSIGAF GGFVVPLAYA 421 WSKVHFGNIE PALHFYVAFF LALLVVTWYC YLRRTTPMGQ VGV //