LOCUS       CAB5247979.1             463 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            integral membrane nitrite extrusion protein naru (nitrite
            facilitator) protein.
ACCESSION   LT708304-278
PROTEIN_ID  CAB5247979.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="narU"
                     /locus_tag="BQ2027_MB0273"
                     /note="Mb0273, narU, len: 463 aa. Equivalent to Rv0267,
                     len: 463 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 463 aa overlap). Probable narU,
                     nitrite extrusion protein, integral membrane protein
                     possibly member of major facilitator superfamily (MFS),
                     similar to other nitrite extrusion proteins e.g.
                     NARU_ECOLI|P37758 nitrite extrusion protein 2 from
                     Escherichia coli (462 aa), FASTA scores: opt: 630, E():
                     4.4e-33, (38.9% identity in 463 aa overlap); and
                     NARK_ECOLI|P10903|B1223 nitrite extrusion protein 1 from
                     Escherichia coli strain K12 (463 aa), FASTA scores: opt:
                     607, E(): 1.3e-31, (42.0% identity in 457 aa overlap).
                     Also similar to Rv0261c, Rv2329c, Rv1737c, and to
                     MLCB22_25 from Mycobacterium leprae (517 aa), FASTA score:
                     (35.1 identity in 459 aa overlap). BELONGS TO THE
                     NARK/NASA FAMILY OF TRANSPORTERS. Protein product from
                     Mb0273 detected using SWATH mass spectrometry."
BEGIN
        1 MALTTAPAID YALPRQQDEG DHWIDDWRPE DPVFWETIGR PIARRNLIFS IFAEHVGFSV
       61 WMLWSIVVVQ MTAAAPGHPA ASGWALSASQ ALCLVAVPSG VGAFLRLPYT FAIPIFGGRN
      121 WTTVSAALLV IPCLLLAWAV SHPSLPFAVL VVIAATAGFG GGNFASSMAN ISFFYPEKDK
      181 GWALGLNAAG GNIGVAVVQK IIPPIVVAGS GVALSRAGLF FVPLAVAAAV CAFLFMNNLT
      241 EAKADVKPVW QSLRHADTWI MSLLYIGTFG SFIGYSAAFP TLLKTVFGRG DIALGWAFLG
      301 AGIGSLVRPL GGKLADRIGG ARITAASFVM LAAGAAAALW SVQSVNLPVF FVSFMFLFVA
      361 TGIGNGSSYR MISRIFQVKG EVAGGDPETM VNMRRQAAGA LGIISSIGAF GGFVVPLAYA
      421 WSKVHFGNIE PALHFYVAFF LALLVVTWYC YLRRTTPMGQ VGV
//