LOCUS       CAB5247975.1             300 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 Allophanate
            hydrolase 2 subunit 2 (EC protein.
ACCESSION   LT708304-274
PROTEIN_ID  CAB5247975.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0269C"
                     /EC_number="3.5.1.54"
                     /note="Mb0269c, -, len: 300 aa. Equivalent to Rv0263c,
                     len: 300 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 300 aa overlap). Conserved
                     hypothetical protein, equivalent to NP_302634.1|NC_002677
                     conserved hypothetical protein from Mycobacterium leprae
                     (305 aa). Also similar to others e.g. AL121596|SC51A_21
                     hypothetical protein from Streptomyces coelicolor (285
                     aa), FASTA scores: opt: 714, E(): 0, (45.3% identity in
                     289 aa overlap); NP_233164.1|NC_002506 conserved
                     hypothetical protein from Vibrio cholerae (309 aa);
                     NP_406216.1|NC_003143 conserved hypothetical protein from
                     Yersinia pestis (316 aa); YH30_HAEIN|P44298|hi1730
                     hypothetical protein from Haemophilus influenzae (309 aa),
                     FASTA scores: opt: 430, E(): 3e-20, (29.6% identity in 284
                     aa overlap); etc. Also similar to carboxylases eg
                     NP_415240.1|NC_000913|P75745|YBGK_ECOLI putative
                     carboxylase from Escherichia coli strain K12 (310 aa),
                     FASTA score: (34.6% identity in 286 aa overlap);
                     NP_459698.1|NC_003197 putative carboxylase from Salmonella
                     typhimurium (310 aa); and to middle part of
                     NP_420636.1|NC_002696 urea amidolyase-related protein from
                     Caulobacter crescentus (1207 aa). Protein product from
                     Mb0269c detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0269c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MTTLEILRSG PLALVEDLGR AGLAHLGVGR SGAADRRSHT LANRLVANPD DWATVEVTFG
       61 GFSARVRGGD VDIAVTGADT DPTVNGIMVG TNSIHHVRDG QVISLGTPRA GLRTYLAVRG
      121 GVCVEPVLGS RSYDVMSAIG PSPLRAGDVL PVGEHTDDYP ELDQAPVAAI EEHLVELRVV
      181 PGPRDDWLVD PDALVHTIWM ASNRSDRVGM RLQGRPLQHR WPDRQLPGEG VTRGAIQVPP
      241 NGLPVILGPD HPITGSYPVV GVITDEDIDK VAQIRPGQYV RLHWARPRSR LPGQGVTQAW
//