LOCUS       CAB5247973.1             469 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            INTEGRAL MEMBRANE NITRITE EXTRUSION PROTEIN NARK3 (NITRITE
            FACILITATOR) protein.
ACCESSION   LT708304-272
PROTEIN_ID  CAB5247973.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="narK3"
                     /locus_tag="BQ2027_MB0267C"
                     /note="Mb0267c, narK3, len: 469 aa. Equivalent to Rv0261c,
                     len: 469 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 469 aa overlap). Probable nirK3,
                     nitrite extrusion protein, integral membrane protein
                     possibly member of major facilitator superfamily (MFS),
                     equivalent to AAB41700.1|U72744 nitrite extrusion protein
                     from Mycobacterium fortuitum (471 aa); and
                     2342627|CAB11406.1|Z98741|T44908 nitrite extrusion protein
                     homolog from Mycobacterium leprae (517 aa; longer in
                     N-terminus). Also similar to other nitrite extrusion
                     proteins e.g. NARK_ECOLI|P10903|B1223 nitrite extrusion
                     protein 1 from Escherichia coli strain K12 (463 aa), FASTA
                     scores: opt: 755, E(): 0, (35.0% identity in 466 aa
                     overlap). BELONGS TO THE NARK/NASA FAMILY OF
                     TRANSPORTERS."
BEGIN
        1 MGRSHQISDW DPEDSVAWEA GNKFIARRNL IWSVAAEHVG FSVWSLWSVM VLFMPTSVYG
       61 FSAGDKFLLG ATATLVGACL RFPYTFATAK FGGRNWTIFS ALVLLIPTVG SILLLANPGL
      121 PLWPYLVCGA LAGLGGGNFA ASMTNINAFF PQRLKGAALA LNAGGGNLGV PMVQLVGLLV
      181 IATAGDREPY WVCAIYLVLL AVAGLGAALY MDNLTEYRIE LNTMRAVVSE PHTWVISLLY
      241 IGTFGSFIGF SFAFGQVLQI NFIASGQSTA QASLHAAQIA FLGPLLGSLS RIYGGKLADR
      301 IGGGRVTLAA FCAMLLATGI LISASTFGDH LAGPMPTATM VGYVIGFTAL FILSGIGNGS
      361 VYKMIPSIFE ARSHSLQISE AERRQWSRSM SGALIGLAGA VGALGGVGVN LALRESYLTS
      421 GTATSAFWAF GVFYLVASVL TWAIYVRRGL KSAGELVPAT TAPAGLAYV
//