LOCUS CAB5247972.1 381 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 possible transcriptional regulatory protein protein. ACCESSION LT708304-271 PROTEIN_ID CAB5247972.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0266C" /note="Mb0266c, -, len: 381 aa. Equivalent to Rv0260c, len: 381 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 381 aa overlap). Possible two-component response regulator, highly similar to CAB72204.1|AL138851 putative transcriptional regulator from Streptomyces coelicolor (395 aa); and similar to O34394|D69851|YJJA conserved hypothetical protein from Bacillus subtilis (270 aa), FASTA scores: opt: 312, E(): 7.4e-14, (25.8% identity in 267 aa overlap). Also some similarity to regulatory proteins at C-terminal region e.g. CUTR_STRLI|Q03756 transcriptional regulatory protein (217 aa), FASTA scores: opt: 138, E(): 0.02, (30.6% identity in 111 aa overlap)." BEGIN 1 MAQAHSAPLT GYRIAVTSAR RAEELCALLR RQGAEVCSAP AIKMIALPDD DELQNNTEAL 61 IADPPDILVA HTGIGFRGWL AAAEGWGLAN ELLESLSSAR IISRGPKATG ALRAAGLREE 121 WSPDSESSHE VLEYLLESGV SRTRIAVQLH GAADSWDPFP EFLGGLRFAG AQVVPIRVYR 181 WKPAPLGGVF DHLVTGIARR QFDAVTFTSA PAAAAVLERS RELDIEDQLL AALRTDVHAM 241 CVGPVTSRPL IRKGVPTSAP ERMRLGALAR HIAEELPLLG SCTFKAAGHV IEIRGTSVLV 301 DDSVKPLSPS GMAILRALVH RPGGVVSRGD LLRVLPGDGS DTHAVDTAVL RLRTALGDKN 361 IVATVVKRGY RLAVDSRHDD V //