LOCUS       CAB5247961.1             273 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 probable
            succinate dehydrogenase [membrane anchor subunit] (succinic
            dehydrogenase) protein.
ACCESSION   LT708304-260
PROTEIN_ID  CAB5247961.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0255C"
                     /note="Mb0255c, -, len: 273 aa. Equivalent to Rv0249c,
                     len: 273 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 273 aa overlap). Probable succinate
                     dehydrogenase, membrane-anchor subunit for succinate
                     dehydrogenase encoded by Rv0247c and Rv0248c. Highly
                     similar to AC44315.1|AL596043 putative integral membrane
                     protein from Streptomyces coelicolor (278 aa). NOTE THAT
                     SUCCINATE DEHYDROGENASE FORMS GENERALLY PART OF AN ENZYME
                     COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN (Rv0248c
                     ?), AN IRON-SULFUR (Rv0247c ?), AND TWO HYDROPHOBIC ANCHOR
                     PROTEINS (Rv0249c ?). Protein product from Mb0255c
                     detected using shotgun mass spectrometry and SWATH mass
                     spectrometry. Mb0255c found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MSAPTANRPA IGVFTPTRAQ IPERTLRTDL WWLPPLLTNL GLLAFICYAT TRAFWGSQYW
       61 VEKYHYLTPF YSPCVSASCQ PGASHLGVWF GHFPGWIPLG AMVLPFLLGF RLTCYYYRKA
      121 YYRSVWQSPT SCAVPEPRAH YTGETRLPLI VQNTHRYFFY IAVVVSLINT YDAIAAFHSP
      181 SGFGFGLGNV ILTINVVLLW AYTISCHSCR HATGGRLKHF SKHPVRYWIW TQVSKLNTRH
      241 MQFAWITLGT LALTDFYIML VASGSITDLR FIG
//