LOCUS       CAB5247957.1             162 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 possible
            oxidoreductase protein.
ACCESSION   LT708304-256
PROTEIN_ID  CAB5247957.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0251"
                     /note="Mb0251, -, len: 162 aa. Equivalent to Rv0245, len:
                     162 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 162 aa overlap). Possible
                     oxidoreductase (EC 1.-.-.-), equivalent to
                     AL022486|MLCB1883_17|T44882 probable oxidoreductase from
                     Mycobacterium leprae (162 aa), FASTA scores: opt: 860,
                     E(): 0, (83.4% identity in 157 aa overlap). Also similar
                     to several hypothetical proteins and various
                     oxidoreductases e.g. AAK24246.1|AE005898 NADH:riboflavin
                     5'-phosphate oxidoreductase from Caulobacter crescentus
                     (174 aa); Q02058|DIM6_STRCO|CAA45048.1 ACTINORHODIN
                     POLYKETIDE DIMERASE from STREPTOMYCES COELICOLOR (177 aa),
                     FASTA scores: opt: 308, E(): 3. 2e-15, (37.8% identity in
                     143 aa overlap). Also similar to
                     Z84498|Rv1939|MTCY09F9.25c from Mycobacterium tuberculosis
                     (171 aa), FASTA scores: opt: 517, E(): 3.5e-30, (49.4%
                     identity in 158 aa overlap). Protein product from Mb0251
                     detected using SWATH mass spectrometry. Mb0251 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MNSTNNLTPS SLREAFGHFP TGVVAIAAEV DGVRQGLAAS TFVPVSLEPP LVSFCVQNTS
       61 TTWPKLTGVP MLGISVLGEA HDAAVRTLAA KTGDRFAGLE TVSNDAGAVF IKGTSVWLES
      121 AIEQLVPAGD HTIVVLRVNQ VKVDPNVAPI VFHRSVLRRL GV
//