LOCUS       CAB5247950.1             204 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 POSSIBLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
            protein.
ACCESSION   LT708304-249
PROTEIN_ID  CAB5247950.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0244"
                     /note="Mb0244, -, len: 204 aa. Equivalent to Rv0238, len:
                     204 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 204 aa overlap). Possible
                     transcriptional regulatory protein, TetR family,
                     equivalent to AL022486|MLCB1883_9|T44874 probable
                     transcription regulator from Mycobacterium leprae (208
                     aa), FASTA scores: opt: 1029, E(): 0, (80.9% identity in
                     199 aa overlap). Also similar to others e.g.
                     CAB77290.1|AL160312 putative tetR-family regulatory
                     protein from Streptomyces coelicolor (240 aa). Also
                     similar to Mycobacterium tuberculosis proteins
                     Z95120|Rv3208 (228 aa), FASTA scores: opt: 266, E():
                     8.3e-12, (28.1% identity in 196 aa overlap); and Rv1019
                     (197 aa). Protein product from Mb0244 detected using SWATH
                     mass spectrometry. Mb0244 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
                     /experiment="experimental evidence, no additional details
                     recorded"
BEGIN
        1 MAGGTKRLPR AVREQQMLDA AVQMFSVNGY HETSMDAIAA EAQISKPMLY LYYGSKEDLF
       61 GACLNREMSR FIDALRSSIN FDQSPKDLLR NTIVSFLRYI DANRASWIVM YTQATSSQAF
      121 AHTVREGREQ IVQLVAELVR AGTRGPLTDA EIEMMAVALV GAGEAVATRL GIGDTDVDEA
      181 AEMMINLFWL GLKGAPVDRL ETGH
//