LOCUS       CAB5247949.1             388 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            CONSERVED LIPOPROTEIN LPQI protein.
ACCESSION   LT708304-248
PROTEIN_ID  CAB5247949.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /gene="lpqI"
                     /locus_tag="BQ2027_MB0243"
                     /note="Mb0243, lpqI, len: 388 aa. Equivalent to Rv0237,
                     len: 388 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (99.7% identity in 388 aa overlap). Probable lpQI,
                     conserved lipoprotein, equivalent to
                     AL022486|MLCB1883_8|T44873 probable secreted hydrolase
                     from Mycobacterium leprae (387 aa), FASTA scores: opt:
                     1831, E(): 0, (73.3% identity in 390 aa overlap). Also
                     similar to other lipoproteins and various hydrolases e.g.
                     P40406|2126897|YBBD_BACSU|I39839 HYPOTHETICAL 70.6 KDA
                     LIPOPROTEIN from Bacillus subtilis (642 aa);
                     P48823|HEXA_ALTSO BETA-HEXOSAMINIDASE A PRECURSOR from
                     ALTEROMONAS SP. (598 aa), FASTA scores: opt: 415, E():
                     5.8e-17, (31.2% identity in 343 aa overlap);
                     PCC6803|P74340 BETA-GLUCOSIDASE from Synechocystis sp.
                     (538 aa), FASTA scores: opt: 414, E(): 6.1e-17, (30.6
                     identity in 320 aa overlap). Contains signal sequence and
                     appropriately positioned PS00013 Prokaryotic membrane
                     lipoprotein lipid attachment site. Protein product from
                     Mb0243 detected using shotgun mass spectrometry and SWATH
                     mass spectrometry. Mb0243 found to be expressed during
                     exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MAFPRTLAIL AAAAALVVAC SHGGTPTGSS TTSGASPATP VAVPVPRSCA EPAGIPALLS
       61 PRDKLAQLLV VGVRDAADAQ AVVTNYHVGG ILIGSDTDLT IFDGALAEIV AGGGPLPLAV
      121 SVDEEGGRLS RLRSLIGGTG PSARELAQTR TVQQVRDLAR DRGRQMRKLG ITIDFAPVVD
      181 VTDAPDDTVI GDRSFGSDPA TVTAYAGAYA QGLRDAGVLP VLKHFPGHGR GSGDSHNGGV
      241 TTPPLDDLVG DDLVPYRTLV TQAPVGVMVG HLQVPGLTGS EPASLSKAAV NLLRTGTGYG
      301 APPFDGPVFS DDLSGMAAIS DRFGVSEAVL RTLQAGADIA LWVTTKEVPA VLDRLEQALR
      361 AGELPMSAVD RSVVRVATMK GPNPGCGR
//