LOCUS CAB5247949.1 388 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE CONSERVED LIPOPROTEIN LPQI protein. ACCESSION LT708304-248 PROTEIN_ID CAB5247949.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /gene="lpqI" /locus_tag="BQ2027_MB0243" /note="Mb0243, lpqI, len: 388 aa. Equivalent to Rv0237, len: 388 aa, from Mycobacterium tuberculosis strain H37Rv, (99.7% identity in 388 aa overlap). Probable lpQI, conserved lipoprotein, equivalent to AL022486|MLCB1883_8|T44873 probable secreted hydrolase from Mycobacterium leprae (387 aa), FASTA scores: opt: 1831, E(): 0, (73.3% identity in 390 aa overlap). Also similar to other lipoproteins and various hydrolases e.g. P40406|2126897|YBBD_BACSU|I39839 HYPOTHETICAL 70.6 KDA LIPOPROTEIN from Bacillus subtilis (642 aa); P48823|HEXA_ALTSO BETA-HEXOSAMINIDASE A PRECURSOR from ALTEROMONAS SP. (598 aa), FASTA scores: opt: 415, E(): 5.8e-17, (31.2% identity in 343 aa overlap); PCC6803|P74340 BETA-GLUCOSIDASE from Synechocystis sp. (538 aa), FASTA scores: opt: 414, E(): 6.1e-17, (30.6 identity in 320 aa overlap). Contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Protein product from Mb0243 detected using shotgun mass spectrometry and SWATH mass spectrometry. Mb0243 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MAFPRTLAIL AAAAALVVAC SHGGTPTGSS TTSGASPATP VAVPVPRSCA EPAGIPALLS 61 PRDKLAQLLV VGVRDAADAQ AVVTNYHVGG ILIGSDTDLT IFDGALAEIV AGGGPLPLAV 121 SVDEEGGRLS RLRSLIGGTG PSARELAQTR TVQQVRDLAR DRGRQMRKLG ITIDFAPVVD 181 VTDAPDDTVI GDRSFGSDPA TVTAYAGAYA QGLRDAGVLP VLKHFPGHGR GSGDSHNGGV 241 TTPPLDDLVG DDLVPYRTLV TQAPVGVMVG HLQVPGLTGS EPASLSKAAV NLLRTGTGYG 301 APPFDGPVFS DDLSGMAAIS DRFGVSEAVL RTLQAGADIA LWVTTKEVPA VLDRLEQALR 361 AGELPMSAVD RSVVRVATMK GPNPGCGR //