LOCUS       CAB5247943.1             229 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR-
            FAMILY) protein.
ACCESSION   LT708304-242
PROTEIN_ID  CAB5247943.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0237"
                     /note="Mb0237, -, len: 229 aa. Equivalent to Rv0232, len:
                     229 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 229 aa overlap). Probable
                     transcriptional regulatory protein, tetR/AcrR family,
                     similar to others e.g. YIXD_BACSU|P32398 hypothetical
                     transcriptional regulator (191 aa), FASTA scores: opt:
                     149, E(): 0.0014, (21.5% identity in 158 aa overlap). Also
                     similar to MTV030_11 from Mycobacterium tuberculosis.
                     Contains PS01081 Bacterial regulatory proteins, tetR
                     family signature, and probable helix-turn helix motif from
                     aa 33-54 (Score 1142, +3.08 SD). BELONGS TO THE TETR/ACRR
                     FAMILY OF TRANSCRIPTIONAL REGULATORS. Mb0237 found to be
                     expressed during exponential growth in Sauton's minimal
                     media by RNA-sequencing."
BEGIN
        1 MPTVTWARVD PARRAAVVEA AEAEFGAHGF SRGSLNVIAR RAGVAKGSLF QYFADKRDLY
       61 AFIADIASQR VRSYMEDLIR ELDPNRPFFE FLTDLLDGWV AYFAEHPRER ALHAAATLEV
      121 DTDARISVRS VLHRHYLDVL RPLVRDAHAR GDLRADSDTG ALMSLLLLIF PHLALAPYMR
      181 GLDPILGLDE PTPEQPALAV RRLVAVLAAA FDAQHPATNS AQTRSEEIT
//