LOCUS CAB5247943.1 229 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR- FAMILY) protein. ACCESSION LT708304-242 PROTEIN_ID CAB5247943.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0237" /note="Mb0237, -, len: 229 aa. Equivalent to Rv0232, len: 229 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 229 aa overlap). Probable transcriptional regulatory protein, tetR/AcrR family, similar to others e.g. YIXD_BACSU|P32398 hypothetical transcriptional regulator (191 aa), FASTA scores: opt: 149, E(): 0.0014, (21.5% identity in 158 aa overlap). Also similar to MTV030_11 from Mycobacterium tuberculosis. Contains PS01081 Bacterial regulatory proteins, tetR family signature, and probable helix-turn helix motif from aa 33-54 (Score 1142, +3.08 SD). BELONGS TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS. Mb0237 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MPTVTWARVD PARRAAVVEA AEAEFGAHGF SRGSLNVIAR RAGVAKGSLF QYFADKRDLY 61 AFIADIASQR VRSYMEDLIR ELDPNRPFFE FLTDLLDGWV AYFAEHPRER ALHAAATLEV 121 DTDARISVRS VLHRHYLDVL RPLVRDAHAR GDLRADSDTG ALMSLLLLIF PHLALAPYMR 181 GLDPILGLDE PTPEQPALAV RRLVAVLAAA FDAQHPATNS AQTRSEEIT //