LOCUS CAB5247939.1 407 aa PRT BCT 25-MAY-2020 DEFINITION Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE INTEGRAL MEMBRANE ACYLTRANSFERASE protein. ACCESSION LT708304-238 PROTEIN_ID CAB5247939.1 SOURCE Mycobacterium tuberculosis variant bovis AF2122/97 ORGANISM Mycobacterium tuberculosis variant bovis AF2122/97 Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex. REFERENCE 1 AUTHORS Malone K.M. JOURNAL Submitted (06-DEC-2016) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine, University College Dublin, D4, Ireland REFERENCE 2 AUTHORS Malone M K., Farrell D., Malone K. JOURNAL Submitted (15-APR-2020) to the INSDC. School of Veterinary Medicine, Tuberculosis Molecular Microbiology Research Group, University College Dublin, Tuberculosis Molecular Microbiology Research Group, School of Veterinary Medicine,, University College Dublin, D4, Ireland FEATURES Qualifiers source /organism="Mycobacterium tuberculosis variant bovis AF2122/97" /chromosome="Mycobacterium_bovis_AF212297" /isolate="AF2122/97" /mol_type="genomic DNA" /isolation_source="Mycobacterium bovis subsp. bovis strain AF2122/97. This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection." /db_xref="taxon:233413" protein /transl_table=11 /locus_tag="BQ2027_MB0233" /note="Mb0233, -, len: 407 aa. Equivalent to Rv0228, len: 407 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 407 aa overlap). Probable integral membrane acyltransferase (EC 2.3.1.-), equivalent to 3063875|CAA18555.1|AL022486|T44870 ACYLTRANSFERASE from Mycobacterium leprae (384 aa), FASTA scores: opt: 2004, E(): 0, (79.3% identity in 381 aa overlap). Also similar to others e.g. Q11064 PROBABLE ACYLTRANSFERASE CY50.28C (383 aa), FASTA scores: opt: 372, E(): 2.6e-16, (35.9% identity in 359 aa overlap); Q00718|MDMB_STRMY ACYLTRANSFERASE. Very similar to Rv0111, Rv1254, etc from Mycobacterium tuberculosis. Mb0233 found to be expressed during exponential growth in Sauton's minimal media by RNA-sequencing." BEGIN 1 MGPADESGAP IRPQTPHRHT VLVTNGQVVG GTRGFLPAVE GMRACAAVGV VVTHVAFQTG 61 HSSGVGGRLF GRFDLAVAVF FAVSGFLLWR GHAAAARDLR SHPRTGPYLR SRVARIMPAY 121 VVAVVVILSL LPDADHASLT VWLANLTLTQ IYVPLTLTGG LTQMWSLSVE VAFYAALPVL 181 ALLGRRIPVG ARVPAIAALA ALSWAWGWLP LDAGSGINPL TWPPAFFSWF AAGMLLAEWA 241 YSPVGLPHRW ARRRVAMAVT ALLGYLVAAS PLAGPEGLVP GTAAQFAVKT AMGSLVAFAL 301 VAPLVLDRPD TSHRLLGSPA MVTLGRWSYG LFIWHLAALA MVFPVIGAFP FTGRMPTVLV 361 LTLIFGFAIA AVSYALVESP CREALRRWER RNEPISVGEL QADAIAP //