LOCUS       CAB5247939.1             407 aa    PRT              BCT 25-MAY-2020
DEFINITION  Mycobacterium tuberculosis variant bovis AF2122/97 PROBABLE
            INTEGRAL MEMBRANE ACYLTRANSFERASE protein.
ACCESSION   LT708304-238
PROTEIN_ID  CAB5247939.1
SOURCE      Mycobacterium tuberculosis variant bovis AF2122/97
  ORGANISM  Mycobacterium tuberculosis variant bovis AF2122/97
            Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
            Mycobacterium; Mycobacterium tuberculosis complex.
REFERENCE   1
  AUTHORS   Malone K.M.
  JOURNAL   Submitted (06-DEC-2016) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine, University College
            Dublin, D4, Ireland
REFERENCE   2
  AUTHORS   Malone M K., Farrell D., Malone K.
  JOURNAL   Submitted (15-APR-2020) to the INSDC. School of Veterinary
            Medicine, Tuberculosis Molecular Microbiology Research Group,
            University College Dublin, Tuberculosis Molecular Microbiology
            Research Group, School of Veterinary Medicine,, University College
            Dublin, D4, Ireland
FEATURES             Qualifiers
     source          /organism="Mycobacterium tuberculosis variant bovis
                     AF2122/97"
                     /chromosome="Mycobacterium_bovis_AF212297"
                     /isolate="AF2122/97"
                     /mol_type="genomic DNA"
                     /isolation_source="Mycobacterium bovis subsp. bovis strain
                     AF2122/97. This strain is a fully virulent strain that was
                     isolated in 1997 in the UK from a cow suffering necrotic
                     lesions in lung and bronchomediastinal lymph nodes. The
                     strain was also reported to infect and persist in badgers
                     that are considered to be a significant source of bovine
                     infection."
                     /db_xref="taxon:233413"
     protein         /transl_table=11
                     /locus_tag="BQ2027_MB0233"
                     /note="Mb0233, -, len: 407 aa. Equivalent to Rv0228, len:
                     407 aa, from Mycobacterium tuberculosis strain H37Rv,
                     (100.0% identity in 407 aa overlap). Probable integral
                     membrane acyltransferase (EC 2.3.1.-), equivalent to
                     3063875|CAA18555.1|AL022486|T44870 ACYLTRANSFERASE from
                     Mycobacterium leprae (384 aa), FASTA scores: opt: 2004,
                     E(): 0, (79.3% identity in 381 aa overlap). Also similar
                     to others e.g. Q11064 PROBABLE ACYLTRANSFERASE CY50.28C
                     (383 aa), FASTA scores: opt: 372, E(): 2.6e-16, (35.9%
                     identity in 359 aa overlap); Q00718|MDMB_STRMY
                     ACYLTRANSFERASE. Very similar to Rv0111, Rv1254, etc from
                     Mycobacterium tuberculosis. Mb0233 found to be expressed
                     during exponential growth in Sauton's minimal media by
                     RNA-sequencing."
BEGIN
        1 MGPADESGAP IRPQTPHRHT VLVTNGQVVG GTRGFLPAVE GMRACAAVGV VVTHVAFQTG
       61 HSSGVGGRLF GRFDLAVAVF FAVSGFLLWR GHAAAARDLR SHPRTGPYLR SRVARIMPAY
      121 VVAVVVILSL LPDADHASLT VWLANLTLTQ IYVPLTLTGG LTQMWSLSVE VAFYAALPVL
      181 ALLGRRIPVG ARVPAIAALA ALSWAWGWLP LDAGSGINPL TWPPAFFSWF AAGMLLAEWA
      241 YSPVGLPHRW ARRRVAMAVT ALLGYLVAAS PLAGPEGLVP GTAAQFAVKT AMGSLVAFAL
      301 VAPLVLDRPD TSHRLLGSPA MVTLGRWSYG LFIWHLAALA MVFPVIGAFP FTGRMPTVLV
      361 LTLIFGFAIA AVSYALVESP CREALRRWER RNEPISVGEL QADAIAP
//